Video: Dab tsi yog cov txheej txheem ntawm kev ua ntawm alteplase?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
CAS Nr.: 105857-23-6
Tsis tas li lo lus nug yog, dab tsi yog qhov txheej txheem ntawm kev txiav txim ntawm TPA?
Mechanism of Action tPA yog thrombolytic (piv txwv li, nws tawg ua ntshav khov) tsim los ntawm kev sib sau ua ke cov platelets qhib rau hauv fibrin meshes los ntawm kev ua kom plasminogen. Tshwj xeeb tshaj yog, nws tshem tawm zymogen plasminogen ntawm nws Arg561-Val562 peptide bond los tsim cov serine protease, plasmin.
Tsis tas li, TPA yog dab tsi thiab nws ua haujlwm li cas? TPA yog cov protein uas tshwm sim ib txwm pom nyob rau ntawm cov qog endothelial, cov cell uas kab cov hlab ntshav. Nws ua rau kev hloov pauv ntawm plasminogen rau plasmin, ib qho enzyme lub luag haujlwm rau kev tawg ntawm cov ntshav txhaws. 2? TPA ua haujlwm los ntawm kev tiv thaiv kev txhaws ntawm cov ntshav txhaws uas cuam tshuam cov ntshav ntws hauv lub hlwb.
Kuj paub, dab tsi yog cov txheej txheem ntawm kev ua ntawm streptokinase?
Streptokinase tsim kom muaj kev ua haujlwm nyuaj uas txhawb nqa kev sib tsoo ntawm Arg/Val daim ntawv cog lus hauv plasminogen los tsim cov proteolytic enzyme plasmin. Plasmin nyob rau hauv lem degrades lub fibrin matrix ntawm lub thrombus, yog li exerting nws thrombolytic. kev ua.
Yam tshuaj twg yog alteplase?
Alteplase yog thrombolytic (THROM-bo-LIT-ik) tshuaj , qee zaum hu ua "clot-busting" tshuaj . Nws pab koj lub cev tsim cov tshuaj uas zom cov ntshav uas tsis xav tau. Alteplase yog siv los kho mob stroke los ntawm cov ntshav txhaws lossis lwm yam kev cuam tshuam hauv cov hlab ntsha.
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