Video: Qhov kev hloov pauv twg yuav ua rau hloov mus rau sab laug hauv cov pa oxygen hemoglobin khi nkhaus?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Cov pa -hemoglobin kev sib cais sib cais tuaj yeem txav chaw xws li qhov kev sib raug zoo rau cov pa oxygen tau hloov pauv. Yam uas hloov pauv nkhaus suav nrog kev hloov pauv cov pa roj carbon dioxide, ntshav kub , ntshav pH, thiab qhov concentration ntawm 2, 3-diphosphoglycerate (2, 3-DPG).
Tom qab ntawd, ib tus tseem tuaj yeem nug, dab tsi ua rau cov pa oxygen hemoglobin nkhaus nkhaus hloov mus rau sab xis?
Kev nce siab ntxiv ntawm BPG hauv cov qe ntshav liab nyiam qhov tsim ntawm T, lub xeev qis qis ntawm hemoglobin cov thiab yog li ntawd cov pa - khi nkhaus yuav hloov mus rau sab xis.
Tsis tas li ntawd, Bohr cuam tshuam dab tsi ntawm oxygen khi rau hemoglobin? Cov Bohr effect tau pom thawj zaug los ntawm kws kho mob lub cev Christian Bohr xyoo 1904. Qhov no nyhuv piav qhia tias hydrogen ions thiab carbon dioxide cuam tshuam li cas rau kev sib raug zoo ntawm cov pa nyob rau hauv Hemoglobin . Yog tias pH qis dua nws ib txwm yog (lub cev ib txwm muaj pH yog 7.4), tom qab ntawd hemoglobin cov tsis khi oxygen ib yam nkaus.
Hauv qhov no, vim li cas cov pa roj carbon monoxide hloov pauv cov pa nkev sib cais mus rau sab laug?
Cov qib hemoglobin- oxygen dissociation nkhaus yog hloov mus rau sab laug , txhais tau tias tsawg dua cov pa tuaj yeem khi rau Hgb ntawm ib nrab cov pa qib siab thiab CO -Hgb tsis tuaj yeem xa cov pa rau cov ntaub so ntswg peripheral zoo (Daim duab 2). Tsis tas li ntawd, CO kuj muaj siab dua khi ua tau zoo rau myoglobin ntau dua cov pa.
Yuav ua li cas carbon monoxide hloov lub hemoglobin oxygen nkhaus?
Modulation ntawm Cov pa - Hemoglobin Kev tsis sib haum xeeb Nkhaus Hypoxia ntev ua rau cov ntshav nce siab ntawm 2, 3-DPG uas tseem ua haujlwm cov nkhaus mus rau sab xis. Lub xub ntiag ntawm HbF thiab carbon monoxide ( CO ) ua haujlwm cov nkhaus mus rau sab laug, nce qhov cov pa affinity ntawm hemoglobin cov.
Pom zoo:
Dab tsi yog txoj haujlwm ntawm sab laug sab laug sab laug?
Hauv tib neeg feem ntau, sab laug ntawm lub paj hlwb yog qhov tseem ceeb, thiab hauv tib neeg feem ntau sab laug sab laug sab laug tswj kev nco txog ntsig txog qhov tseeb thiab cov ntaub ntawv, nrog rau lub peev xwm paub lub ntsej muag thiab khoom
Dab tsi yog kev hloov pauv sab laug hauv qhov nkhaus sib cais oxyhemoglobin hu ua?
Cov xwm txheej no hloov pauv lossis hloov pauv qhov nkhaus ntawm kev sib cais oxyhemoglobin. Kev hloov pauv sab xis qhia tias hemoglobin hauv kev tshawb fawb tau txo qis kev nyiam rau oxygen. Kev ua haujlwm sab laug ntawm txoj kab nkhaus yog ib qho cim ntawm hemoglobin kev sib raug zoo ntxiv rau oxygen (piv txwv li ntawm lub ntsws)
Yam twg ntawm cov hauv qab no yog qhov hloov pauv hloov pauv tau rau kev mob pob txha?
Yam yuav hloov pauv tau yam muaj xws li: Dej cawv. Kev haus luam yeeb. Low Body Mass Index. Kev noj zaub mov tsis zoo. Vitamin D tsis txaus. Kev noj zaub mov tsis zoo. Estrogen tsis muaj peev xwm. Kev tawm dag zog tsis txaus
Dab tsi ua rau sab laug hloov pauv hauv oxyhemoglobin nkhaus?
Kev ua haujlwm sab laug ntawm txoj kab nkhaus yog ib qho cim ntawm hemoglobin kev sib raug zoo ntxiv rau oxygen (piv txwv li ntawm lub ntsws). fetal hemoglobin muaj O2 siab dua li cov neeg laus hemoglobin; Feem ntau vim qhov txo qis affinity rau 2,3-bisphosphoglycerate
Dab tsi ua rau cov pa oxygen dissociation nkhaus hloov mus rau sab xis?
Qhov nce ntawm qhov kub hloov pauv qhov nkhaus mus rau sab xis, thaum qhov ntsuas kub poob qis hloov txoj kab nkhaus mus rau sab laug. Ua kom qhov kub thiab txias denatures kev sib raug zoo ntawm oxygen thiab hemoglobin, uas ua rau kom cov pa oxygen thiab hemoglobin thiab txo cov concentration ntawm oxyhaemoglobin