Video: Lub luag haujlwm ntawm c3 yog dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Cov C3 noob muab cov lus qhia rau ua cov protein hu ua kev tiv thaiv ntxiv 3 (lossis C3 ). Cov protein no ua lub luag haujlwm tseem ceeb hauv ib feem ntawm lub cev kev tiv thaiv kab mob hu ua kev ua kom tiav.
Yooj yim li ntawd, vim li cas c3 tseem ceeb?
Cov protein no yog ib feem ntawm koj qhov kev ua tiav, ib qho tseem ceeb ib feem ntawm koj lub cev tiv thaiv kab mob uas pab tua kab mob ua rau muaj kab mob thiab kab mob. Ua ke tivthaiv C3 yog tshaj plaws tseem ceeb thiab muaj protein ntau nyob hauv cov txheej txheem ntxiv. Nws tau muab tso rau ntawm cov kab mob me me kom rhuav tshem lawv.
Ib yam nkaus, c3a thiab c5a ua dab tsi? C3a thiab C5a , qhov me me (kwv yees li 10KDa) qhov tawg tawg tawm los ntawm kev ua kom tiav, yog cov kws kho mob muaj zog ntawm kev mob. Lawv yog cov tshuaj anaphylatoxins thiab ua lub cell activators nrog nanomolar affinity, ua haujlwm lawv los ntawm kev khi rau cov neeg txais tshwj xeeb (C3aR thiab C5aR lossis C5L2 feem).
Ib yam nkaus, tib neeg nug, c3 hloov pauv ua dab tsi?
C3 convertase tau siv los hais txog daim ntawv tsim tawm hauv txoj hauv kev hloov pauv (C3bBb) lossis cov txheej txheem qub thiab qhuab qhia (C4bC2b, yav dhau los C4b2a). Ib zaug tsim, ob qho tib si C3 hloov pauv yuav catalyze proteolytic cleavage ntawm C3 rau hauv C3a thiab C3b (yog li lub npe " C3 - hloov dua siab tshiab ").
Siab c3 txhais li cas?
C3 thiab C4, raws li cov protein ntshav tseem ceeb ntawm txoj hauv kev ntxiv, ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob21. Siab qib ntawm C3 yuav ua rau siab C3a thiab C5a, cov tshuaj anaphylatoxins no kho cov txheej txheem ua mob los ntawm kev ua ntawm lawv tus kheej cov neeg txais khoom (C3aR thiab C5aR)36, 37.
Pom zoo:
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