Video: Puas yog aminoglycosides muaj qhov nqaim kho qhov ntsuas?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Feem ntau cov tshuaj tua kab mob, xws li β-lactams, macrolides thiab quinolones muaj ib dav kho qhov ntsuas thiab yog li ntawd ua tsis xav tau kho tshuaj xyuas. Qee qhov, xws li aminoglycosides thiab vancomycin tshuaj , muaj qhov kho qhov muag nqaim , thiab tshuaj lom tuaj yeem ua rau hnyav thiab hloov tsis tau.
Raws li, puas yog gentamicin muaj qhov ntsuas nqaim kho?
Zoo li lwm yam aminoglycosides, gentamicin muaj qhov kho qhov muag nqaim thiab kho tshuaj xyuas muaj pov thawj kom muaj txiaj ntsig, tshwj xeeb hauv cov neeg muaj kev pheej hmoo xws li cov neeg laus. Txawm li cas los xij, qhov tseem ceeb dua yog lub sijhawm ntawm kev kho aminoglycoside thiab kev siv ua ke ntawm lwm cov tshuaj nephrotoxic tshuaj.
Ib tus kuj yuav nug, puas yog theophylline muaj qhov ntsuas nqaim kho? Theophylline muaj qhov kho qhov muag nqaim ; kho cov concentration yog nruab nrab ntawm 10 thiab 20Μg/ml. Nws yog demethylated thiab hydroxylated hauv lub siab, thiab tshem tawm los ntawm ob lub raum. Ib nrab-lub neej hauv cov neeg laus yog txog 5 teev. Yog li ntawd, yuav tsum tau saib xyuas cov ntshav ntau ntau thiab kho qhov koob tshuaj yog tias tsim nyog.
Tom qab ntawd, lo lus nug yog, cov tshuaj twg muaj qhov ntsuas nqaim kho?
Tshuaj nrog a nqaim kho qhov ntsuas 4 Peb tau txhais cov hauv qab no tshuaj to NTI- tshuaj : aminoglycosides, ciclosporin, carbamazepine, digoxin, digitoxin, flecainide, lithium, phenytoin, phenobarbital, rifampicin, theophylline thiab warfarin.
Puas yog phenytoin muaj qhov ntsuas nqaim kho?
Phenytoin yog antiepileptic tus neeg sawv cev uas yog zoo rau tonic-clonic thiab focal qaug dab peg 1. Nws muaj qhov kho qhov muag nqaim thiab kev sib raug zoo ntawm koob tshuaj thiab ntshav qab zib phenytoin siab yog tsis yog tawm
Pom zoo:
Tus pas ntsuas ntsuas ntsuas ntsuas ntsuas ntsuas yog dab tsi?
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Puas yog phenytoin muaj qhov ntsuas nqaim kho?
Phenytoin yog ib qho tshuaj tua kab mob uas ua tau zoo rau tonic-clonic thiab focal seizures 1. Nws muaj qhov ntsuas kho mob nqaim thiab kev sib raug zoo ntawm koob tshuaj thiab cov tshuaj phenytoin concentration tsis yog tawm
Dab tsi yog qhov ntsuas qhov ntsuas qhov ntsuas?
Kev ntsuas qhov ncauj hais lus yog cov cuab yeej muaj zog siv los ntsuas qhov kev paub mob. Kev ntsuas qhov ntsuas qhov hais lus, tseem hu ua cov qhab nia ntawm qhov mob thiab cov lus piav qhia qhov ntsuas, yog cov ntawv qhia tus kheej uas muaj ntau cov lus uas tsim los piav txog qhov mob hnyav thiab lub sijhawm (Karcioglu li al., 2018)
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Cov qhab nias thiab txhais lus CAS muaj 21 yam khoom nrog 4 qhov kev xaiv txhua tus (uas tau qhab nia 0,1,2,3). CAS tus qhab nia tsuas yog qhov sib npaug ntawm cov qhab nia khoom. Yog li, cov qhab nia ntawm CAS tuaj yeem nyob ntawm 0 txog 63. Qhov qhab nia siab dua txhais tau tias tus neeg koom nrog muaj cov tsos mob npau taws ntau dua