BCR hauv microbiology yog dab tsi?

2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44

B-cell tus txais ( BCR ) yog tsim los ntawm cov tshuaj tiv thaiv kab mob immunoglobulin uas tsim hom 1 transmembrane receptor protein feem ntau nyob ntawm sab nrauv ntawm hom lymphocyte hu ua B cells. Tshwj xeeb, pab pawg thiab nthuav tawm nce kev sib raug zoo ntawm antigen nrog BCR , yog li ua pov thawj rhiab heev thiab ua kom nrov nrov.

Dhau li, qhov sib txawv ntawm qhov tshuaj tiv thaiv kab mob thiab BCR B cell receptor) yog dab tsi?

Lub ntsiab qhov sib txawv ntawm B cell receptor thiab tshuaj tiv thaiv kab mob yog lub B cell receptor yog transmembrane receptor ntawm cov B hlwb qhov twg tshuaj tiv thaiv kab mob yog protein molecule uas yog B hlwb tsim khoom Cov B hlwb yog ib ntawm ob hom ntawm lymphocytes uas cov pob txha tsim tawm.

Ib tus kuj tseem yuav nug tau tias, qib twg ntawm immunoglobulins tuaj yeem siv ua BCR? Immunoglobulin D IgD yog monomer nrog lub cev hnyav ntawm 184 Kd. IgD uas tam sim no muaj me ntsis hauv cov ntshav (0.03 mg/mL) thiab muaj qhov tsis paub ua haujlwm tiv thaiv kab mob. Nws yog suav tias yog ib qho BCR . IgD tuaj yeem ua lub luag haujlwm tseem ceeb hauv antigen-triggered lymphocyte sib txawv.

Qhov ntawd, 5 hom immunoglobulins yog dab tsi thiab lawv lub luag haujlwm yog dab tsi?

Feem ntau sau luv ua "Ig," cov tshuaj tiv thaiv kab mob tau pom hauv cov ntshav thiab lwm cov kua hauv lub cev ntawm tib neeg thiab lwm yam tsiaj txhu. Lawv pab txheeb xyuas thiab rhuav tshem cov khoom txawv teb chaws xws li kab mob me me (piv txwv li, kab mob, kab mob protozoan thiab kab mob). Immunoglobulins tau muab cais ua tsib pawg: IgA, IgD, IgE, IgG thiab IgM.

Dab tsi yog qhov tshuaj tiv thaiv kab mob yooj yim txhais?

Antibodies (tseem hu ua immunoglobulins) yog cov loj Y-cov protein uas tuaj yeem lo rau saum cov kab mob thiab kab mob. Lawv pom nyob hauv cov ntshav lossis lwm yam kua hauv lub cev ntawm cov nqaj qaum. Txhua tus tshuaj tiv thaiv kab mob yog txawv. Lawv txhua tus tau tsim los tua tsuas yog ib hom antigen (hauv kev coj ua, qhov no txhais tau tias yog tus kab mob lossis kab mob).