Video: Vim li cas cov zis calcium tsawg hauv Fhh?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
TSEV KAWM NTAWV: FHH yog tshwm sim los ntawm inactivating mutations nyob rau hauv lub calcium sensing receptor (CASR) noob ua rau dav dav calcium -mob siab rau, them nyiaj rau hypercalcemia thiab hypocalciuria. Tus yam ntxwv yog tus raug cov zis calcium tsawg excretion nyob rau hauv sib piv rau PHPT, nyob rau hauv uas tso zis calcium kev tso tawm ntau ntxiv.
Hais txog qhov no, dab tsi ua rau cov zis muaj calcium tsawg?
Yog cov zis calcium ntau ntau siab dhau lawm os qis , tej zaum nws yuav txhais tau tias koj muaj mob, xws li mob raum lossis pob zeb raum. Feem ntau lub raum pob zeb yog tsim los ntawm calcium . Ntau dhau lossis tsawg dhau calcium hauv cov ntshav kuj tuaj yeem qhia tau tias muaj mob raum, nrog rau qee yam kab mob ntawm pob txha, thiab lwm yam teeb meem kho mob.
Tom qab ntawd, lo lus nug yog, Fhh tsawg npaum li cas? Feem ntau, FHH (hom-1) yog tshwm sim los ntawm kev tsis ua haujlwm hloov pauv hauv cov noob encoding cov tshuaj calcium uas paub txog tus neeg txais khoom (CASR) qhia hauv cov parathyroids thiab ob lub raum. Kwv yees li ntawm FHH yog 1 ntawm 78 000 piv nrog thawj hyperparathyroidism ntawm 1 hauv 1000.
Cov lus nug tseem yog, dab tsi ua rau calcium hauv cov zis kuaj?
A calcium urine test kuj tseem tuaj yeem pab koj tus kws kho mob nkag siab tias vim li cas koj thiaj siab calcium qib hauv koj cov ntshav. Tej zaum koj yuav hnov koj tus kws kho mob lossis tus kws saib xyuas neeg mob hu qhov no "hypercalcemia." Feem ntau ua ntawm tus mob no yog qog ua parathyroid ntau dhau. Tsawg calcium qib tuaj yeem cuam tshuam ntau PTH ntau lawm los ntawm cov qog parathyroid.
Fhh yog dab tsi?
Tsev neeg hypocalciuric hypercalcemia ( FHH ) yog feem ntau asymptomatic caj ces tsis sib xws ntawm phosphocalcic cov metabolism ua rau lub cev nyob ntev nrog hypercalcemia nrog rau normo- lossis hypocalciuria thiab nce ntshav parathyroid hormone (PTH) siab.
Pom zoo:
Vim li cas cov kws tshawb fawb ntxig cov noob rau tib neeg cov insulin rau hauv cov kab mob?
Recombinant DNA yog cov kws tshawb fawb thev naus laus zis tsim los uas ua rau nws muaj peev xwm ntxig tib neeg cov noob mus rau hauv cov khoom siv ntawm cov kab mob sib kis. Qhov "recombinant" micro-organism tam sim no tuaj yeem tsim cov protein nkag los ntawm tib neeg cov noob. Cov kws tshawb fawb tsim tib neeg cov insulin insulin hauv chav kuaj
Cov qog twg hauv qab no ua rau cov qib calcium ntau ntxiv hauv cov ntshav?
Cov parathyroid hormone (PTH), zais los ntawm cov qog parathyroid, yog lub luag haujlwm tswj hwm qib calcium hauv ntshav; nws tau tso tawm thaum twg cov ntshav calcium qib qis. PTH nce cov ntshav calcium ntau ntau los ntawm kev txhawb nqa osteoclasts, uas ua rau cov pob txha tawg kom tso calcium rau hauv cov ntshav
Dab tsi ua rau cov piam thaj hauv cov zis hauv cov dev?
Thaum cov piam thaj hauv ntshav nce mus txog qib ib, cov zis ntau dhau raug tshem tawm los ntawm ob lub raum thiab nkag mus rau cov zis. Qhov no yog vim li cas cov dev thiab cov neeg muaj ntshav qab zib mellitus muaj suab thaj hauv lawv cov zis (glucosuria) thaum lawv cov insulin qis
Qhov muaj pes tsawg ntawm cov muaju hauv cov zis yog dab tsi?
Cov theem ib txwm ntawm cov zis oxalate excretion yog tsawg dua 45 milligrams ib hnub (mg / hnub). Qib siab ntawm cov zis oxalate tuaj yeem txhais tau tias koj muaj kev pheej hmoo ntawm kev tsim pob zeb hauv lub raum. Kev pheej hmoo ntawm kev tsim pob zeb zoo li nce ntxiv txawm tias qib siab tshaj 25 mg/hnub, uas suav tias yog qib ib txwm muaj
Yog vim li cas cov zis concentration hauv Siadh?
Cov zis osmolality: Hauv SIADH, cov ADH ntau dhau ua rau cov dej nyob hauv, tab sis tsis daws cov dej huv. Raws li qhov tshwm sim, cov zis ntau nyob hauv cov sodium tau tsim tawm, txawm tias tsis muaj cov ntshav sodium tsawg