Video: Puas yog fluconazole muaj zog cyp3a4 inhibitor?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Fluconazole yog ib inhibitor ntawm CYP3A4 , CYP2C9 thiab 2C19 enzymes tab sis tsis yog inhibitor ntawm cov neeg thauj khoom [10, 12, 15]. Yog li ntawd, cov teebmeem ntawm fluconazole ntawm PK ntawm 5-HMT yuav suav hais tias yog tus sawv cev ntawm kev sib cuam tshuam ntawm Nruab nrab CYP3A4 inhibitors nrog fesoterodine.
Hauv qhov no, dab tsi yog qhov muaj zog cyp3a4 inhibitors?
Muaj peev xwm inhibitors ntawm CYP3A4 suav nrog clarithromycin erythromycin, diltiazem, itraconazole, ketoconazole , ritonavir, verapamil, goldenseal thiab txiv kab ntxwv qaub. Inducers ntawm CYP3A4 suav nrog phenobarbital, phenytoin, rifampicin, St. John's Wort thiab glucocorticoids.
Ib yam li ntawd, cov tshuaj dab tsi cuam tshuam nrog Diflucan? Kev kho mob lossis muaj peev xwm tseem ceeb cuam tshuam nrog kev siv tshuaj ntawm DIFLUCAN thiab cov neeg sawv cev hauv qab no/chav kawm tau pom thiab tau piav qhia ntau dua hauv qab no:
- Alfentanil.
- Amiodarone hmoov.
- Amitriptyline, nortriptyline.
- Amphotericin B.
- Astemizole.
- Azithromycin.
- Calcium channel blockers.
- Carbamazepine.
Ntawm no, yog voriconazole muaj zog cyp3a4 inhibitor?
Tag nrho cov azoles inhibit cov CYP3A4 isoenzyme (daim duab 1). Ntxiv rau CYP3A4 , fluconazole thiab voriconazole yog thiab muaj zog noncompetitive lossis mixed-type inhibitors ntawm CYP2C9 thiab CYP2C19 [27, 43, 44].
Puas yog Diflucan txaus ntshai?
Muaj tsawg zaus, cov neeg mob kho nrog Diflucan tuaj yeem tsim kev phom sij plawv atherosclerosis abnormalities los yog kev tsis haum tshuaj loj. Diflucan feem ntau tsis pom zoo rau cov poj niam cev xeeb tub lossis cov niam laus.
Pom zoo:
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