Video: Yuav ua li cas cytotoxic T cells tsim?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
CD8+ (NCO+ cytotoxic tshuaj ) T hlwb , zoo li CD4+ Pab T hlwb , yog tsim tawm hauv thymus thiab qhia tawm T - ntawm tes tus txais. Txawm li cas los xij, tsis yog CD4 molecule, cytotoxic T hlwb nthuav tawm tus lej sib luag, CD8, feem ntau yog tsim los ntawm ib CD8α thiab ib qho CD8β saw.
Raws li, cov cytotoxic T cells qhib li cas?
Cytotoxic T cells yog qhib los ntawm dendritic hlwb uas qhia txog antigen-loaded class I molecules. Dendritic hlwb noj intact hlwb (cross-priming) los yog dawb antigens. Lub teeb liab thib ob yog muab los ntawm CD28 rau T hlwb cuam tshuam nrog B7-1 ntawm antigen-presenting hlwb.
Qhov thib ob, puas cytotoxic T cells tsim cytokines? Feem ntau cytotoxic T hlwb qhia T - ntawm tes receptors (TCRs) uas ua tau paub txog ib qho antigen tshwj xeeb. Ib qho antigen yog ib qho molecule uas muaj peev xwm txhawb kev tiv thaiv kab mob, thiab feem ntau ua los ntawm mob qog noj ntshav hlwb lossis kab mob. Txawm li cas los xij, CD8+ T hlwb kuj muaj peev xwm ua tau qee yam cytokines.
Kuj nug, yuav ua li cas T cells thiaj li qhib tau?
Pab T cells dhau los ua haujlwm Thaum lawv tau nthuav tawm nrog peptide antigens los ntawm MHC chav kawm II molecules, uas tau nthuav tawm nyob rau saum npoo ntawm antigen-presenting. hlwb (APCs). Ib zaug qhib , lawv faib sai thiab zais cov cytokines uas tswj lossis pab tiv thaiv kev tiv thaiv kab mob.
Lub luag haujlwm ntawm T cytotoxic cells quizlet yog dab tsi?
Cytotoxic T cells tua tej qog hlwb thiab hloov cov ntaub so ntswg hlwb , zoo li hlwb kis los ntawm microbes. Cytotoxic T cells tua lub hom phiaj lub cev hlwb zoo li ntuj tua neeg hlwb ua.
Pom zoo:
Cytotoxic T cells nyob qhov twg?
CD8+ (cytotoxic) T cells, zoo li CD4+ Helper T cells, tau tsim hauv cov thymus thiab nthuav tawm T-cell receptor. Txawm li cas los xij, ntau dua li CD4 molecule, cytotoxic T cells nthuav qhia qhov dimeric co-receptor, CD8, feem ntau yog tsim los ntawm ib CD8α thiab ib CD8β saw
Nyob rau theem dab tsi ntawm kev tsim cov kab mob fungal yog diploid cells tsim?
Hauv lub neej voj voog ntawm kev sib deev kis tus kab mob hu ua fungus, theem haploid hloov nrog qib diploid. The haploid theem xaus nrog nuclear fusion, thiab theem diploid pib nrog kev tsim zygote (diploid cell ua los ntawm fusion ntawm ob haploid cells)
Cytotoxic T cells ua haujlwm li cas?
Cytotoxic CD8 T cells ua tiav lawv txoj haujlwm tua los ntawm kev tso ob hom preformed cytotoxic protein: cov granzymes, uas zoo li tuaj yeem ntxias apoptosis hauv txhua hom phiaj ntawm tes, thiab pore-forming protein perforin, uas xuas qhov rau hauv lub hom phiaj-cell membrane los ntawm cov granzymes tuaj yeem nkag mus
Qhov sib txawv ntawm tus pab T cells thiab cytotoxic T cells yog dab tsi?
T hlwb yog li ntawd hu ua vim lawv feem ntau tsim nyob rau hauv lub thymus. Raws li cov npe hais tias pab T hlwb 'pab' lwm lub hlwb ntawm lub cev tiv thaiv kab mob, thaum cytotoxic T hlwb tua cov kab mob kis kab mob thiab qog. Tsis zoo li cov tshuaj tiv thaiv kab mob, TCR tsis tuaj yeem khi cov tshuaj tiv thaiv ncaj qha
Lub luag haujlwm tseem ceeb ntawm cytotoxic T cells yog dab tsi?
Cytotoxic T lymphocytes (CTLs) sawv cev rau ib ntawm ob peb hom cell ntawm lub cev tiv thaiv kab mob uas muaj peev xwm tua ncaj qha rau lwm cov cell. Lawv ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv tus tswv tsev tiv thaiv kab mob, nrog rau kev kis kab mob los ntawm lwm cov kab mob hauv lub cev uas rov ua dua hauv cytoplasm ntawm tus tswv tsev cell