Video: Yuav ua li cas yog ob lub compartment qauv nyob rau hauv pharmacokinetics?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Pharmacokinetic ob - qauv qauv . Pharmacokinetics hais txog tus nqi thiab qhov twg ntawm kev faib tshuaj rau cov ntaub so ntswg sib txawv, thiab tus nqi ntawm kev tshem tawm cov tshuaj. Lub peripheral qhov chaw ( chav tsev 2 ) muaj cov ntaub so ntswg uas qhov kev faib tawm ntawm cov tshuaj qeeb dua.
Ib yam li ntawd, nws yog nug, dab tsi yog ob qho qauv ntawm lub cev muaj pes tsawg leeg?
Figure 1: Cov ob - compartment qauv ntawm lub cev muaj pes tsawg leeg . Raws li qhov no qauv , tib neeg lub cev tau muab faib ua cov rog tivthaiv thiab tsis muaj rog. Lub cev rog tuaj yeem muab faib ntxiv rau ob pawg, uas yog cov roj tseem ceeb thiab cov roj cia. Cov roj tseem ceeb yog tsim nyog rau qhov qub lub cev ua haujlwm.
Tsis tas li ntawd, piv txwv ntawm pharmacokinetics yog dab tsi? Digoxin, tshwj xeeb tshaj yog thaum muab intravenously, yog ib qho piv txwv ntawm ib qho tshuaj uas tau piav qhia zoo los ntawm ob-compartment pharmacokinetics . Tom qab txhaj tshuaj intravenously, plasma concentrations nce thiab tom qab ntawd poob sai sai vim tias cov tshuaj faib tawm ntawm cov ntshav plasma thiab mus rau hauv cov leeg nqaij.
Tsis tas li ntawd, dab tsi yog ib qho piv txwv ntawm ib qho qauv?
Cov ib - qhov chaw qhib qauv yog qhov yooj yim tshaj plaws los piav txog cov txheej txheem ntawm kev faib tshuaj thiab tshem tawm hauv lub cev. Qhov no qauv xav tias cov tshuaj tuaj yeem nkag mus lossis tawm hauv lub cev (piv txwv li, lub qauv yog "qhib"), thiab tag nrho lub cev ua haujlwm zoo li ib leeg, tsis sib xws qhov chaw.
Dab tsi yog 5 txoj cai pharmacokinetic?
Kev txhais ntawm Pharmacokinetics Lawv yog nqus, faib, metabolism, thiab tso tawm.
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