Vim li cas cov tshuaj tiv thaiv kab mob khi rau cov antigens tshwj xeeb?
Vim li cas cov tshuaj tiv thaiv kab mob khi rau cov antigens tshwj xeeb?

Video: Vim li cas cov tshuaj tiv thaiv kab mob khi rau cov antigens tshwj xeeb?

Video: Vim li cas cov tshuaj tiv thaiv kab mob khi rau cov antigens tshwj xeeb?
Video: Qhia cub tshuaj tiv thaiv kab mob li cas Feb 13/2021 2024, Lub rau hli ntuj
Anonim

Cov tshuaj tiv thaiv lees paub qhov tshwj xeeb ntawm lub hom phiaj txawv teb chaws, hu ua ib qho antigen . Txhua qhov taw qhia ntawm "Y" ntawm ib qho tshuaj tiv thaiv muaj paratope uas yog tshwj xeeb rau ib tshwj xeeb epitope (zoo ib yam rau lub xauv thiab qhov tseem ceeb) ntawm ib qho antigen , tso cai rau ob lub qauv no khi ua ke nrog precision.

Tsis tas li ntawd, yuav ua li cas tom qab cov tshuaj tiv thaiv khi ib qho antigen tshwj xeeb?

Thaum twg qee yam tshuaj tiv thaiv ua ke nrog antigens , lawv qhib qhov cascade ntawm cuaj cov protein, hu ua kev sib ntxiv, uas tau nthuav dav hauv daim ntawv tsis ua haujlwm hauv cov ntshav. Ua tiav daim ntawv koom tes nrog tshuaj tiv thaiv , ib zaug lawv tau teb nrog antigen , los pab rhuav tshem cov neeg tawm tsam txawv teb chaws thiab tshem tawm ntawm lub cev.

Tsis tas li ntawd, cov tshuaj tiv thaiv yuav ua li cas thiaj paub cov antigens tshwj xeeb? Immunogens tuaj yeem tsim los ua li ntawd tshuaj tiv thaiv yog tsim tawm tsam tshwj xeeb cov proteins. Cov tshwj xeeb cheeb tsam ntawm ib antigen tas ib antibody paub thiab khi rau yog hu ua epitope, los yog antigenic tus txiav txim. Ib qho epitope feem ntau yog 5-8 amino acids ntev ntawm cov protein.

Hauv qhov no, kev sib raug zoo ntawm antigens thiab cov tshuaj tiv thaiv yog dab tsi?

Antigens yog cov lwg me me muaj peev xwm txhawb kev tiv thaiv kab mob. Txhua antigen muaj qhov sib txawv ntawm qhov chaw, lossis epitopes, ua rau cov lus teb tshwj xeeb. Cov tshuaj tiv thaiv (immunoglobins) yog cov protein zoo li Y tsim los ntawm B cells ntawm lub cev tiv thaiv kab mob los teb rau kis antigens.

Tus qauv ntawm cov tshuaj tiv thaiv kab mob tso cai rau nws khi rau cov antigen tshwj xeeb li cas?

Txhua tshuaj tiv thaiv muaj plaub lub polypeptides- ob lub saw hnyav thiab ob lub teeb saw txuas ntxiv los ua ib qho "Y" zoo li cov molecule. Cov cheeb tsam no sib txawv, muaj li ntawm 110-130 amino acids, muab cov tshuaj tiv thaiv nws tshwj xeeb rau khi antigen.

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