![Puas yog DPP 4 inhibitors muaj kev nyab xeeb? Puas yog DPP 4 inhibitors muaj kev nyab xeeb?](https://i.answers-medical.com/preview/medical-health/14035801-are-dpp-4-inhibitors-safe-j.webp)
Video: Puas yog DPP 4 inhibitors muaj kev nyab xeeb?
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2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Hauv qhov xaus, DPP - 4 cov tshuaj tiv thaiv zoo li ib nyab xeeb Kev xaiv rau cov neeg mob uas muaj ntshav qab zib hom 2 xws li kev kho mob monotherapy lossis kev kho mob ntxiv. Txawm li cas los xij, tsis muaj kev txiav txim siab zoo tuaj yeem kos ntawm tus kheej DPP - 4 cov tshuaj tiv thaiv vim tsis muaj lub taub hau mus sim.
Tsis tas li ntawd, DPP 4 inhibitor ua dab tsi?
Lub mechanism ntawm DPP - 4 cov tshuaj tiv thaiv yog kom nce qib incretin (GLP-1 thiab GIP), uas inhibit glucagon tso tawm, uas nyob rau hauv lem nce insulin secretion, txo lub plab khoob, thiab txo cov ntshav qabzib.
Qhov thib ob, DPP 4 inhibitors puas txo qis insulin tsis kam? Hauv qhov xaus, DPP - 4 cov tshuaj tiv thaiv raws li kev kho mob monotherapy lossis ntxiv rau kev kho mob tau txhim kho beta-cell ua haujlwm tau zoo tab sis tsis muaj qhov cuam tshuam loj rau insulin tsis kam hauv hom 2 mob ntshav qab zib. DPP - 4 yog lub luag haujlwm rau kev puas tsuaj ntawm cov tshuaj hormones incretin xws li glucagon zoo li peptide 1 (GLP-1)8.
Ntxiv rau qhov no, cov piv txwv ntawm DPP 4 inhibitors yog dab tsi?
DPP - 4 cov tshuaj tiv thaiv yog chav kawm ntawm cov tshuaj uas siv nrog kev noj zaub mov thiab tawm dag zog los tswj ntshav qab zib hauv cov neeg laus uas muaj ntshav qab zib hom 2. Tshuaj nyob rau hauv DPP - 4 ua inhibitor chav kawm muaj xws li sitagliptin, saxagliptin, linagliptin, thiab alogliptin.
Puas yog Metformin yog DPP 4 inhibitor?
Cov txheej txheem tseem ceeb nce qib GLP-1 los ntawm metformin tseem yuav tsum tau tsim thaum kawg; nws tau hais tias yuav tshwm sim los ntawm txwv tsis pub ntawm DPP - 4 (Lindsay et al 2005; Mannucci et al 2001), Txawm hais tias tseem muaj kev tshawb pom tias metformin tsis cuam tshuam DPP - 4 kev ua si (Hinke et al 2002).
Pom zoo:
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