Cov txheej txheem:
Video: Qee qhov piv txwv ntawm aminoglycosides yog dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Piv txwv ntawm aminoglycosides suav nrog:
- Gentamicin (generic version yog IV nkaus xwb)
- Amikacin (IV nkaus xwb)
- Tobramycin.
- Gentak thiab Genoptic (qhov muag dauv)
- Kanamycin.
- Streptomycin.
- Neo-Fradin (qhov ncauj)
- Neomycin (generic version yog IV nkaus xwb)
Tsuas yog li ntawd, kab mob dab tsi ua aminoglycosides kho?
Aminoglycosides yog ib chav kawm ntawm cov tshuaj tua kab mob siv feem ntau hauv cov kev kho mob ntawm aerobic gram-negative bacilli kab mob , txawm hais tias lawv tseem muaj txiaj ntsig zoo rau lwm tus kab mob suav nrog Staphylococci thiab Mycobacterium tuberculosis. Lawv feem ntau siv ua ke nrog lwm cov tshuaj tua kab mob.
Ib qho tseem yuav nug, cov tshuaj tua kab mob aminoglycoside ua haujlwm li cas? Aminoglycosides muaj zog bactericidal tshuaj tua kab mob uas ua los ntawm kev txwv tsis pub cov protein sib sau ua ke, yog li khi cov kab mob 30S lossis 50S ribosomal subunit, txwv tsis pub hloov pauv ntawm peptidyl-tRNA los ntawm A-site mus rau P-site, thiab tseem ua rau nyeem tsis raug ntawm mRNA.
Tsis tas li kom paub yog, uas aminoglycoside tuaj yeem noj qhov ncauj?
Aminoglycosides siv tam sim no hauv Tebchaws Meskas suav nrog streptomycin , gentamicin , tobramycin , amikacin , plazomicin thiab neomycin . Cov aminoglycosides tau nqus tsis zoo ntawm qhov ncauj thiab feem ntau tau muab rau niam txiv, xws li los ntawm txhaj tshuaj lossis txhaj tshuaj.
Aminoglycosides npog dab tsi?
Aminoglycosides yog muaj zog bactericidal tshuaj tua kab mob uas ua los ntawm kev tsim fissures nyob rau hauv lub txheej membrane ntawm cov kab mob ntawm tes. Lawv yog tshwj xeeb tshaj yog tawm tsam aerobic, gram-negative kab mob thiab ua synergistically tiv thaiv qee yam kab mob gram-zoo.
Pom zoo:
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