Video: Leptin receptors nyob qhov twg?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Leptin receptor (Ob-R) isoforms.
Qhov ntev, tag nrho cov isoform ntawm Ob-Rb yog qhia feem ntau nyob rau hauv lub hypothalamus, qhov twg nws koom nyob rau hauv zoghomeostasis thiab nyob rau hauv cov kev cai ntawm secretory organs'activity.
Ib yam li ntawd, nyob qhov twg cov leptin receptors nyob?
Tsis muaj kev ncig, ua haujlwm nquag, leptin cov tshuaj hormones ua rau muaj kev rog loj heev raws li pom hauv ob/obmice. Leptin inhibits kev noj zaub mov thiab nce zog siv nyiaj los ntawm kev sib cuam tshuam nrog tshwj xeeb leptin receptors tau txav chaw hauv hypothalamus.
Leptin yog dab tsi thiab nws ua haujlwm li cas? Leptin Kev tswj cov txheej txheem metabolic thiab thov kom nws ua rau koj lub hlwb paub tias muaj pes tsawg rog hauv koj lub cev cov leptin theem nce, koj qab los noj mov diminishes. Raws li leptin theem poob, koj qab los noj mov nce. Nws tswj tus nqi ntawm cov rog rog.
Raws li, leptin khi rau dab tsi?
Leptin txuas ( binds) rau thiab qhib cov aprotein hu ua leptin receptor, haum rau lub receptor zoo li tus yuam sij rau hauv lub xauv. Cov cov leptin receptor protein yog pom nyob rau saum npoo ntawm cov hlwb hauv ntau lub cev thiab cov ntaub so ntswg ntawm lub cev nrog rau ib feem ntawm lub hlwb hu ua thehypothalamus.
Dab tsi yog DB db nas?
Kuj Paub Raws Li: BKS db mus homozygous rau cov ntshav qab zib tshwm sim hloov pauv (Lepr db ua ) ua rau pom kev mob qog noj ntshav, mob ntshav qab zib ntev, ua rau pancreatic beta cell atrophy thiab dhau los ua cov tshuaj insulin.
Pom zoo:
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