Video: Myasthenic thiab cholinergic ntsoog yog dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Cholinergic teebmeem cov txiaj ntsig los ntawm qhov ntau ntawm cholinesterase inhibitors (piv txwv li, neostigmine, pyridostigmine, physostigmine) thiab zoo ib yam li organophosphate lom. Ob leeg myasthenic ntsoog thiab cholinergic ntsoog tuaj yeem ua rau hnoos hawb pob, hnoos hawb pob, ua pa tsis ua haujlwm, diaphoresis, thiab cyanosis.
Ib yam li ntawd, koj yuav nug, dab tsi yog cholinergic ntsoog?
A cholinergic ntsoog yog kev txhawb siab dhau ntawm kev sib tshuam neuromuscular vim muaj ntau tshaj ntawm acetylcholine (ACh), vim yog qhov tsis ua haujlwm (tej zaum txawm tias cholinesterase inhibitor) ntawm AChE enzyme, uas ib txwm zom acetylcholine.
Tsis tas li, koj kho tus mob cholinergic ntsoog li cas? Ib qho teeb meem cholinergic yuav tsum tau kho los ntawm kev tshem tawm tag nrho cov tshuaj anticholinesterase, tshuab cua tshuab yog tias xav tau, thiab atropine i.v. rau cov teebmeem muscarinic ntawm kev noj tshuaj ntau dhau. Cov neuromuscular thaiv yog cov nyhuv nicotinic thiab yuav tsis hloov pauv los ntawm atropine.
Tom qab ntawd, dab tsi yog cholinergic ntsoog thiab dab tsi yog nws cov tsos mob Nws kho li cas?
Kev qaug zog thiab ntxhov siab hauv cholinergic ntsoog tuaj yeem yog kho nrog benzodiazepine zoo li midazolam lossis lorazepam. Kev saib xyuas yuav tsum tau ua kom tsis txhob muaj tshuaj xws li lub voj diuretics, theophylline, thiab caffeine thiab succinylcholine hauv tshuaj lom organophosphate vim qhov no tuaj yeem ua rau tsos mob ntawm toxicity zuj zus.
Dab tsi ua rau muaj cov nyhuv cholinergic?
Taw qhia. Cholinergic toxicity yog ua los ntawm kev siv tshuaj, tshuaj, thiab tshuaj uas txhawb, txhim kho lossis ua raws li tus kab mob neurotransmitter acetylcholine tshuaj . Acetylcholine yog thawj neurotransmitter ntawm parasympathetic paj hlwb.
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