Video: Vim li cas thiaj siv spironolactone hauv mob qog noj ntshav?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Spironolactone yog aldosterone antagonist, ua rau feem ntau ntawm cov tubules nyob deb kom nce natriuresis thiab khaws cov poov tshuaj. Spironolactone yog cov tshuaj uas xaiv hauv thawj qhov kev kho mob ntawm ascites vim cirrhosis.
Tsis tas li ntawd, vim li cas thiaj siv spironolactone hauv kab mob siab?
Spironolactone yog aldosterone receptor antagonist thiab potassium-sparing diuretic dav siv hauv kev kho mob edema, tshwj xeeb hauv cov neeg mob nrog cirrhosis nyob rau hauv uas hyperaldosteronism tshwm los ua lub luag haujlwm tseem ceeb. Spironolactone tau txuas rau qhov xwm txheej tsis tshua muaj tshwm sim ntawm cov tshuaj pom los ntawm kev siv tshuaj kab mob siab.
Ib yam nkaus, dab tsi ntawm theem kab mob cirrhosis ascites tshwm sim? Ascites yog qhov teeb meem loj ntawm cirrhosis , 3 thiab lub sijhawm nruab nrab rau nws txoj kev txhim kho yog kwv yees li 10 xyoo. Ascites yog lub cim tseem ceeb hauv kev nce qib mus rau hauv qhov decompensated theem ntawm cirrhosis thiab cuam tshuam nrog kev ua tsis zoo thiab lub neej zoo; kev tuag yog kwv yees li 50% hauv 2 xyoos.
Tsuas yog li ntawd, yam tshuaj diuretic twg feem ntau pom zoo rau cov neeg mob cirrhosis?
Spironolactone
Vim li cas aldosterone nce siab cirrhosis?
Cov tshuaj renin-angiotensin aldosterone hmoov (RAA) cov txheej txheem yog li txhawb nqa thiab ob lub raum khaws cov kua ua lub hauv paus hauv tsev los kho ECF thiab cov ntshav tag nrho. Yog li ntawd tej zaum yuav muaj nce lub raum tubular rhiab heev rau aldosterone hmoov nyob rau hauv cirrhosis.
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