Cov epitopes pom nyob qhov twg?

2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44

Txhua ntawm cov tshuaj tiv thaiv kab mob no khi rau qhov tshwj xeeb epitope nyob ntawm cov protein. Kev khi ntawm cov tshuaj tiv thaiv kab mob thiab epitope ua tshwm sim ntawm Antigen Binding Site, uas yog hu ua paratope thiab yog nyob ntawm qhov kawg ntawm cheeb tsam sib txawv ntawm cov tshuaj tiv thaiv kab mob.

Yooj yim li ntawd, cov epitopes tau tsim los li cas?

Epitope . Ib epitope ua , tseem hu ua antigenic determinant, yog ib feem ntawm antigen uas tau lees paub los ntawm lub cev tiv thaiv kab mob, tshwj xeeb los ntawm cov tshuaj tiv thaiv kab mob, B cells, lossis T cells. Ib tug raws epitope ua yog tsim los ntawm 3-D kev hloov pauv tau pom zoo los ntawm kev cuam tshuam ntawm qhov tsis sib xws ntawm cov amino acid seem.

dab tsi yog qhov ua haujlwm ntawm epitope? Epitope , tseem hu ua antigenic determinant, feem ntawm cov protein txawv teb chaws, lossis antigen, uas muaj peev xwm txhawb kev tiv thaiv kab mob. Ib epitope ua yog ib feem ntawm cov antigen uas khi rau ib qho tshwj xeeb antigen receptor nyob rau saum npoo ntawm B cell.

Hauv qhov no, epitopes ua los ntawm dab tsi?

Tawm cov epitopes feem ntau yog ib txwm muaj los ntawm sequential amino acids uas koom nrog hauv kev tiv thaiv kab mob tiv thaiv kab mob thiab lawv cov kev cuam tshuam yog ua raws thawj qhov qauv ntawm epitope ua . CD8 T-xov tooj cov epitopes nthuav tawm los ntawm MHC I cov lwg me me feem ntau yog cov kab peptides nrog qhov ntev uas txawv ntawm 8 txog 11 cov amino acids.

Muaj pes tsawg epitopes puas muaj antigen?

Cov naj npawb ntawm cov epitopes nyob ntawm qhov piv txwv ntawm qhov loj ntawm antigen . Rau tib neeg cov protein nws muaj tau txiav txim siab tias cov epitopes tau suav nrog 9 txog 22 cov amino acids, tsis tas yuav tsum txuas ntxiv, tab sis tsawg kawg nyob ze thaum cov protein tau muab tais.