Video: Kab mob diphtheria ua rau cov nqaij puas tsuaj li cas?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Diphtheria toxin yog dab tsi ? Diphtheria toxin (DT) yog exotoxin tsim los ntawm cov kab mob sib kis ntawm Corynebacterium diphtheriae cov kab mob, uas nws kis tau ua mob caj pas thiab ua npaws, ua raws li necrosis ntawm kev ua pa cov ntaub so ntswg uas tsim cov yam ntxwv tuab tuab lub tsho tiv no.
Hauv qhov no, qhov mob diphtheria toxin muaj txiaj ntsig dab tsi?
Diphtheria toxin tuaj yeem ncig hauv cov ntshav thiab cuam tshuam lub plawv thiab CNS systems. Myocarditis, nrog rau lub plawv o, circulatory vau, lub plawv tsis ua hauj lwm, AV thaiv thiab dysrhythmias. Nervous system kuj tuaj yeem koom nrog suav nrog kev tuag tes tuag taw ntawm qhov muag, qhov muag tsis pom kev. Lawv daws nrog daws teeb meem kev kis mob.
Tom qab ntawd, lo lus nug yog, diphtheria toxin tua cov cell li cas? Diphtheria toxin tua cov cell los ntawm inhibiting eukaryotic protein synthesis, thiab nws cov txheej txheem ntawm kev ua tau nthuav dav. Cov haujlwm ADP-ribosylation ntawm diphtheria toxin yog txiav txim siab tag nrho los ntawm A fragment, thiab tsis muaj feem ntawm B fragment yog xav tau rau kev ua haujlwm catalytic.
Ua li no, tus mob diphtheria toxin ua haujlwm li cas?
Diphtheria toxin yog exotoxin zais cia los ntawm Corynebacterium, cov kab mob pathogenic uas ua rau diphtheria . Cov tshuaj lom ua rau tus kab mob hauv tib neeg los ntawm kev nkag mus rau hauv cell cytoplasm thiab inhibiting protein synthesis.
Cov kab mob diphtheria lom los qhov twg los?
Diphtheria toxin yog zais cia los ntawm Corynebacterium diphtheriae raws li cov kab mob polypeptide ib leeg muaj ob lub ntsiab lus tseem ceeb: DT-A, uas nqa qhov chaw nyab xeeb rau ADP ribosylation ntawm EF-2, thiab DT-B, uas txhawb kev khi ntawm tshuaj lom rau cov cell thiab nkag ntawm A saw mus rau hauv cytosolic compartment.
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