Video: Dab tsi yog congenital teeb meem ntawm glycosylation?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Congenital teeb meem ntawm glycosylation (CDG) yog pab pawg uas tau txais cov metabolism hauv teeb meem uas cuam tshuam rau txheej txheem hu ua glycosylation . Glycosylation yog txheej txheem nyuaj uas txhua tus tib neeg lub hlwb tsim cov piam thaj ntev uas txuas nrog cov protein, uas hu ua glycoproteins. CDG hom IA yog daim ntawv tshaj plaws.
Ib yam nkaus, uas yog ib qho piv txwv ntawm teeb meem thaum yug?
Piv txwv ntawm feem ntau yam ntxwv congenital ntshawv siab Congenital plawv tsis xws luag suav nrog patent ductus arteriosus, atrial septal defect, ventricular septal defect, thiab tetralogy ntawm Fallot. Cev xeeb tub anomalies ntawm lub paj hlwb suav nrog neural tube tsis xws luag xws li spina bifida, encephalocele, thiab anencephaly.
Ib tus kuj tseem yuav nug, CDG muaj ntau npaum li cas? Zoo li cas Puas yog Teeb Meem Tsis Txaus Siab ntawm Glycosylation Hom Ia? CDG -Ia suav txog 70% ntawm cov menyuam tsis sib xws ntawm glycosylation, uas ua ke cuam tshuam rau 1 ntawm txhua 50, 000 txog 100, 000 yug. Cov CDG -Ia tau tshaj tawm thoob ntiaj teb, nrog txog ib nrab los ntawm cov tebchaws Scandinavian.
Ib sab saum toj, dab tsi ua rau glycosylation?
Raws li tau tham los saum no, CDG yog ua los ntawm qhov tsis txaus lossis tsis muaj cov enzymes tshwj xeeb koom nrog kev tsim cov ntoo qab zib (glycans) thiab lawv cov kev khi rau lwm cov protein lossis lipid ( glycosylation ). Glycosylation yog txheej txheem dav thiab nyuaj. Piv txwv, PMM2-CDG yog ua los ntawm kev hloov pauv ntawm PMM2 noob.
Puas yog CDG tuag taus?
Kev yug menyuam tsis zoo ntawm glycosylation qee zaum hu ua CDG cov tsos mob. Lawv feem ntau ua rau mob hnyav, qee zaum tuag , kev ua haujlwm tsis zoo ntawm ob peb lub cev sib txawv (tshwj xeeb yog lub paj hlwb, cov leeg, thiab cov hnyuv) hauv cov menyuam mos uas cuam tshuam.
Pom zoo:
Lub zog daws teeb meem ntawm lub teeb tsom yog dab tsi?
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