Lub ntsiab lus ntawm aminoglycosides yog dab tsi?

2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44

Kev kho mob Kev txhais ntawm aminoglycoside

: ib yam ntawm pab pawg ntawm cov tshuaj tua kab mob (zoo li streptomycin thiab neomycin) uas txwv tsis pub cov kab mob sib xyaw ua ke cov protein thiab ua haujlwm tshwj xeeb rau cov kab mob gram-negative.

Xav txog qhov no, aminoglycosides ua haujlwm li cas?

Mechanism of action Ib zaug hauv cov kab mob hu ua cell, aminoglycosides siv lawv cov kev cuam tshuam los ntawm kev khi rau ribosomes, organelles uas yog qhov tseem ceeb rau kev sib txuas ntawm cov protein. Vim li ntawd, cov protein synthesis raug txwv, thiab cov kab mob cell tuag.

Tom qab ntawd, lo lus nug yog, ob qho kev phiv loj ntawm aminoglycosides yog dab tsi? Qhia rau koj tus menyuam tus kws kho mob lossis kws saib xyuas neeg mob paub sai li sai tau yog tias koj tus menyuam muaj ib yam ntawm cov kev mob tshwm sim no:

• tsis hnov lus.
• nrov nrov lossis nrov nrov hauv pob ntseg.
• kev xav ntawm kev ua tiav ntawm pob ntseg.
• nce nqhis dej.
• xav kom tso zis ntau dua lossis tsawg dua li ib txwm.
• ntawm daim tawv nqaij los yog khaus.
• tsaug zog txawv txav, kiv taub hau, lossis tsis muaj zog.

Cov lus nug tseem yog, dab tsi yog qee qhov piv txwv ntawm aminoglycosides?

Piv txwv ntawm aminoglycosides suav nrog:

• Gentamicin (generic version yog IV nkaus xwb)
• Amikacin (IV nkaus xwb)
• Tobramycin.
• Gentak thiab Genoptic (qhov muag poob)
• Kanamycin.
• Streptomycin.
• Neo-Fradin (qhov ncauj)
• Neomycin (generic version yog IV nkaus xwb)

Aminoglycosides ua dab tsi?

Aminoglycosides yog cov tshuaj tua kab mob muaj zog tua kab mob uas ua los ntawm kev tsim fissures hauv txheej sab nrauv ntawm cov kab mob ntawm tes. Lawv tshwj xeeb tshaj yog tawm tsam aerobic, kab mob gram-tsis zoo thiab ua haujlwm sib koom tes tiv thaiv qee yam kab mob gram-positive.