Video: Cov tshuaj twg dhau los ua ntej dhau cov metabolism?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Thawj dhau cov metabolism tej zaum yuav tshwm sim hauv lub siab (rau propranolol, lidocaine, chloromethiasole thiab GTN) lossis hauv lub plab (rau benzylpenicillin thiab insulin). Tom qab a tshuaj yog nqos, nws tau nqus los ntawm lub plab zom mov thiab nkag mus rau hauv lub cev hepatic portal.
Qhov tseeb, vim li cas cov tshuaj thiaj li dhau mus dhau cov metabolism?
Thawj - Pass Effect . Hepatic thawj zaug dhau tshwm sim thaum tshuaj yog absorbed los ntawm txoj hnyuv metabolized los ntawm cov enzymes hauv daim siab mus rau qhov zoo uas feem ntau ntawm cov neeg sawv cev nquag ua tsis tawm ntawm lub siab thiab, yog li ntawd, ua tsis ncav cuag cov kev ncig (Daim duab 1).
Ib sab saum toj no, puas yog paracetamol nkag mus thawj zaug cov metabolism? Paracetamol ( acetaminophen ) yog ib qho tshuaj antipyretic thiab analgesic ntau heev. Nws tau nqus tau zoo tom qab kev tswj hwm qhov ncauj, nrog kev noj qab haus huv ntawm 70-90% ua rau thawj dhau cov metabolism [17, 18, 19].
Ib sab saum toj no, ua cov tshuaj IV puas tau hla thawj cov metabolism?
Thawj dhau cov metabolism txiav txim siab seb qhov feem ntawm qhov ncauj yuav mus txog qhov ncig - qhov feem bioavailable. Tshuaj txhaj tshuaj tsis txhob ua qhov no thawj dhau cov nyhuv thiab yog, los ntawm kev txhais, 100% bioavailable. Tshuaj tswj qhov ncauj lossis nqus pa qhia tau tias tsawg dua 100% kev noj qab haus huv.
Qhov twg thawj zaug dhau cov metabolism tshwm sim?
Cov tshuaj tau nqus los ntawm cov kab mob GI thiab dhau ntawm cov hlab ntsha portal mus rau hauv lub siab qhov twg qee cov tshuaj tau metabolized. Qee zaum qhov tshwm sim ntawm thawj dhau cov metabolism txhais tau tias tsuas yog ib feem ntawm cov tshuaj mus txog qhov ncig. Thawj dhau cov metabolism tau tshwm sim hauv lub cev thiab lub siab.
Pom zoo:
Cov ntsiav tshuaj daim ntawv twg muaj cov txheej tshwj xeeb uas tiv thaiv lub plab acid thiab ua rau cov tshuaj yaj hauv cov hnyuv?
Cov txheej txheej enteric yog cov txheej txheem polymer siv rau ntawm cov tshuaj hauv qhov ncauj uas tiv thaiv nws txoj kev tawg lossis tsis tawg hauv ib puag ncig lub plab
Kuv yuav ua li cas dhau los kuv thawj zaug dhau cov metabolism hauv?
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