Video: Dab tsi yog txhais los ntawm lo lus glycosylation muab piv txwv?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Feem ntau, glycosylation yog cov tshuaj tiv thaiv kab mob uas cov carbohydrates (tus pub glycosyl) txuas rau hydroxyl lossis lwm pab pawg ua haujlwm ntawm tus txais glycosyl. Lub npe hu ua carbohydrates glycan ua . Piv txwv ntawm glycoconjugates yog glycolipids thiab glycoproteins.
Tom qab ntawd, koj txhais li cas los ntawm glycosylation?
Glycosylation (saib cov tshuaj glycosylation ) yog cov tshuaj tiv thaiv uas muaj cov carbohydrates, piv txwv li tus pub dawb glycosyl, txuas nrog hydroxyl lossis lwm pab pawg ua haujlwm ntawm lwm cov qauv (tus txais glycosyl). Aglycosylation yog tus yam ntxwv ntawm kev tsim cov tshuaj tiv thaiv kab mob kom hla dhau glycosylation.
Ntxiv mus, glycosylation yog dab tsi thiab nws tshwm sim nyob qhov twg? Cov protein glycosylation yog ib qho tshuaj tiv thaiv tshuaj tiv thaiv kab mob enzyme uas yog qhov chaw hauv ER (Endoplasmic Reticulum) thiab hauv Golgi Apparatus lub cev ntawm tes. General glycosylation hauv ER pab nrog folding, thiab glycosylation hauv Golgi lub cev qhia cov protein uas yuav mus qhov twg.
Ua li no, glycosylation yog dab tsi thiab vim li cas nws thiaj tseem ceeb?
Glycosylation yog ib tseem ceeb thiab cov txheej txheem tswj tau zoo ntawm kev ua cov protein thib ob hauv cov cell. Nws ua lub luag haujlwm tseem ceeb hauv kev txiav txim siab cov qauv protein, ua haujlwm thiab ruaj khov. Cov kev hloov pauv hauv cov txheej txheem no ua rau muaj kev hloov pauv li cas lawv nrhiav neeg ua haujlwm, sib cuam tshuam thiab qhib cov lus qhia rau cov protein (piv txwv li G cov protein).
Vim li cas cov protein glycosylated?
Protein glycosylation pab ua kom haum ntawm cov protein , kev ruaj ntseg thiab hauv xov tooj ntawm tes mus rau cov xovtooj ntawm tes feem ntau xav tau los ntawm cov cell ntawm lub cev tiv thaiv kab mob. Qhov chaw loj ntawm protein glycosylation hauv lub cev yog ER, Golgi lub cev, lub hauv paus thiab cov kua dej ntawm tes.
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