![Lub luag haujlwm ntawm fibrillin 1 yog dab tsi? Lub luag haujlwm ntawm fibrillin 1 yog dab tsi?](https://i.answers-medical.com/preview/medical-health/13938993-what-is-the-normal-function-of-fibrillin-1-j.webp)
Video: Lub luag haujlwm ntawm fibrillin 1 yog dab tsi?
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2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Fibrillin - 1 yog qhov loj, cov txheej txheem sab nrauv uas tsis pub dhau lub cev glycoprotein uas ua haujlwm ua cov txheej txheem ntawm 10-12 nm calcium-khi microfibrils. Cov microfibrils no muab lub zog txhawb nqa cov txheej txheem txhawb nqa hauv cov ntaub so ntswg thiab tsis sib txuas thoob plaws lub cev.
Cov lus nug tseem yog, qhov haujlwm ntawm fibrillin 1 yog dab tsi?
Li qub Muaj nuj nqi FBN1 noob muab cov lus qhia rau ua cov protein loj hu ua fibrillin - 1 . Cov protein no tau thauj tawm ntawm cov cell mus rau hauv cov txheej txheem sab nrauv, uas yog cov kab sib txuas sib xyaw ntawm cov protein thiab lwm yam molecules uas tsim nyob hauv qhov chaw nruab nrab ntawm cov cell.
Tsis tas li, fbn1 sawv rau dab tsi? Ua Tsis Muag Kuv Cov Ntaub Ntawv Tus Kheej.
Hauv qhov no, fibrillin pom nyob qhov twg?
Fibrillin-1 Txog hnub tim, 3 daim ntawv ntawm fibrillin tau piav qhia. Cov protein fibrillin-1 tau raug cais los ntawm Engvall xyoo 1986, thiab kev hloov pauv hauv FBN1 noob ua rau Marfan syndrome. Cov protein no tau pom hauv tib neeg, thiab nws cov noob tau pom ntawm chromosome 15. Tam sim no ntau tshaj 1500 qhov kev hloov pauv sib txawv tau piav qhia.
Dab tsi chromosome cuam tshuam los ntawm Marfan syndrome?
Kev hloov pauv hauv FBN1 lossis fibrillin noob ntawm chromosome 15 ua rau muaj teeb meem caj ces hu ua Marfan syndrome. Lub misshapen protein los ntawm mutated noob ua rau cov leeg tsis muaj zog, ligaments thiab lwm cov nqaij txuas hauv lub cev.
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