Video: Tsis tshua muaj pes tsawg Fhh?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Kwv yees li ntawm FHH yog 1 ntawm 78 000 piv nrog cov thawj hyperparathyroidism ntawm 1 ntawm 1000. Tsawg kawg 234 kev hloov pauv tau piav qhia hauv CASR gene thiab ua rau muaj cov phenotypes xws li normocalcemia mus rau pronounced hypercalcemia.
Zoo sib xws, Fhh yog dab tsi?
Tsev neeg hypocalciuric hypercalcemia ( FHH ) yog feem ntau asymptomatic caj ces tsis sib xws ntawm phosphocalcic cov metabolism ua rau lub cev nyob ntev nrog hypercalcemia nrog rau normo- lossis hypocalciuria thiab nce ntshav parathyroid hormone (PTH) siab.
Tsis tas li ntawd, puas yog hypercalcemia genetic? Hereditary yam. Tsawg tsawg caj teeb meem paub tias yog tsev neeg hypocalciuric hypercalcemia ua rau kom muaj cov calcium ntau ntxiv hauv koj cov ntshav vim yog ua tsis tau zoo ntawm cov receptors calcium hauv koj lub cev. Tus mob no tsis ua rau cov tsos mob lossis teeb meem ntawm hypercalcemia.
Qhov tseeb, vim li cas cov zis calcium tsawg hauv Fhh?
TSEV KAWM NTAWV: FHH yog tshwm sim los ntawm inactivating mutations nyob rau hauv lub calcium sensing receptor (CASR) noob ua rau dav dav calcium -mob siab rau, them nyiaj rau hypercalcemia thiab hypocalciuria. Tus yam ntxwv yog tus raug cov zis calcium tsawg excretion nyob rau hauv sib piv rau PHPT, nyob rau hauv uas tso zis calcium kev tso tawm ntau ntxiv.
Cov qib calcium hauv cov zis ib txwm yog dab tsi?
Li qub cov txiaj ntsig Tus nqi ntawm calcium hauv tso zis ntawm ib tug noj a li qub noj zaub mov yog 100 mus rau 300 milligrams ib hnub (mg / hnub). Kev noj zaub mov uas tsawg calcium tau txais 50 mus rau 150 mg / hnub ntawm calcium hauv tso zis.
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