Qhov sib txawv ntawm acetylcholine thiab acetylcholinesterase yog dab tsi?

2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44

Acetylcholine : tshuaj lom neeg neurotransmitter pom dav hauv lub cev. Acetylcholinesterase (feem ntau hu ua Cov tshuaj cholinesterase ): ib qho enzyme uas cuam tshuam sai sai rau kev xa xov paj hlwb, acetylcholine tshuaj , yog li nws tsis dhau-txhawb nqa tom qab synaptic qab haus huv, leeg, thiab qog qog.

Tsis tas li, acetylcholine txawv ntawm acetylcholinesterase li cas?

Acetylcholinesterase yog koom nrog hauv hydrolysis ntawm acetylcholine tshuaj , qhov tseem ceeb neurotransmitter ntawm lub hauv paus paj hlwb, rau hauv choline (Daim duab 9). Qhov enzyme catalyzes hydrolysis ntawm cov neurotransmitter acetylcholine tshuaj ntawm neuronal synapses, thiab ntawm neuromuscular junctions, thaum kawg ntawm cov txheej txheem teeb liab.

dab tsi yog lub luag haujlwm acetylcholinesterase? Acetylcholinesterase . Acetylcholinesterase (HGNC cim ACHE; EC 3.1. 1.7), tseem hu ua AChE lossis acetylhydrolase, yog thawj cov tshuaj cholinesterase hauv lub cev. Nws yog ib qho enzyme uas txhawb kev tawg ntawm acetylcholine tshuaj thiab ntawm qee qhov lwm cov choline esters uas muaj nuj nqi raws li neurotransmitters.

Tom qab ntawd, lo lus nug yog, puas yog cholinesterase thiab acetylcholinesterase tib yam?

Ob hom Cov tshuaj cholinesterase yog acetylcholinesterase tshuaj (ACHE) thiab butyrylcholinesterase (BCHE). Qhov sib txawv ntawm ob hom tau ua nrog lawv cov kev nyiam rau cov substrates: cov qub hydrolyses acetylcholine tshuaj sai dua; tom kawg hydrolyses butyrylcholine sai dua.

Acetylcholinesterase puas tawg acetylcholine rau hauv?

Acetylcholinesterase pom nyob rau hauv lub synapse ntawm paj hlwb thiab cov leeg hlwb. Nws tos ntev thiab caij nplooj ntoo hlav rau hauv ua sai sai tom qab lub teeb liab dhau mus, tawg ntej le acetylcholine rau hauv nws ob feem, acetic acid thiab choline.