![Lub neej ib nrab ntawm CellCept yog dab tsi? Lub neej ib nrab ntawm CellCept yog dab tsi?](https://i.answers-medical.com/preview/medical-health/13959806-what-is-the-half-life-of-cellcept-j.webp)
Video: Lub neej ib nrab ntawm CellCept yog dab tsi?
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2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Pharmacological chav kawm: Immunosuppressive tshuaj
Xav txog qhov no, ib nrab lub neej ntawm mycophenolate yog dab tsi?
Qhov siab tshaj plaws ntshav plasma mycophenolic acid concentration (C.max) qab a mycophenolate mofetil 1g koob tshuaj rau cov tib neeg noj qab haus huv yog nyob ib ncig ntawm 25 mg / L, tshwm sim ntawm 0.8 teev tom qab noj tshuaj, lwj nrog qhov pom meej meej. ib nrab - lub neej (t1/2) ntawm ib ncig ntawm 16 teev, thiab tsim ib qho chaw nruab nrab ntawm lub plasma concentration-time nkhaus (AUC
Ib tug kuj yuav nug, dab tsi yog kev phiv ntawm CellCept? Cov kev mob tshwm sim feem ntau yuav muaj xws li:
- plab tsis xis nyob, xeev siab, ntuav, raws plab, cem quav;
- o ntawm koj lub pob taws lossis ko taw;
- pob khaus;
- mob taub hau, kiv taub hau, tshee;
- ua npaws, mob caj pas, lossis lwm yam kab mob;
- cov qe ntshav qis; los yog.
- nce ntshav siab lossis lub plawv dhia.
Tsis tas li, nws siv sijhawm ntev npaum li cas rau CellCept kom tawm ntawm koj lub cev?
Hauv cov neeg laus noj qab haus huv uas tsis xeeb tub, nws siv sijhawm nruab nrab ntawm ib lub lim tiam rau feem ntau ntawm cov mycophenolate yuav ploj mus koj lub cev . Yog tias koj tab tom npaj cev xeeb tub, tham nrog koj kws kho mob txog thaum koj yuav tsum tso tseg cov tshuaj no thiab cov kev kho mob.
Puas yog CellCept txaus ntshai?
Kev noj tshuaj zoo li CellCept, uas ua rau lub cev tsis muaj zog, tuaj nrog ntau yam txaus ntshai. Ntau yam ntawm cov kev mob tshwm sim muaj mob me me thiab tsis mob hnyav, tab sis qee qhov hnyav, txaus ntshai, thiab tej zaum yuav ua rau lub neej hem. Xyoo 2009 Roche tshaj tawm rau FDA tias muaj cov neeg mob ntshav liab dawb aplasia hauv qee tus neeg siv cov tshuaj.
Pom zoo:
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Isotope lub neej ib nrab yog 13.22 teev; qhov lwj los ntawm kev siv lub tshuab hluav taws xob mus rau tellurium-123 tso tawm gamma hluav taws xob nrog lub zog tseem ceeb ntawm 159 keV (qhov no yog gamma feem ntau siv rau kev yees duab)
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Peak concentrations tau ua raws li kev poob qis hauv lub cev nrog kev tshem tawm ib nrab-lub neej (t0. 5) ntawm 4.03 teev. Ntawm koob tshuaj 8 mg/kg, Cmax ntawm 776 ng/ml tau mus txog 1.7 teev tom qab txhaj tshuaj. Ib nrab-tshem tawm ntawm 8 mg/kg yog 5.47 teev
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Thaum Lantus tau pib ua ntej, nws tau ua lag luam raws li '24-teev-insulin,' tab sis, nrog ib nrab-lub neej ntawm 12 teev, insulin glargine ib txwm tawm tsam kom ua raws li qhov kev cog lus ntawd thiab tau pom nws tus kheej los ntawm kev ua haujlwm ntev insulin degludec (Tresiba, Novo Nordisk), uas tau muaj nyob hauv European Union txij li Lub Ib Hlis
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Lub paj hlwb sab hauv suav nrog txhua lub paj hlwb hauv lub cev uas nyob sab nraud ntawm tus txha caj qaum thiab lub hlwb. Cov hlab ntsha no nqa cov ntaub ntawv mus rau thiab los ntawm lub hauv nruab nrab lub paj hlwb kom muab txoj haujlwm ntawm lub cev. Sensory hlwb koom nrog hauv kev noj cov ntaub ntawv los ntawm lub periphery mus rau hauv nruab nrab lub paj hlwb
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