Video: T lymphocytes mus qhov twg tom qab tawm ntawm cov thymus?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Tsis paub qab hau T lymphocytes txav los ntawm pob txha pob txha mus rau hauv thymus ua qhov twg lawv dhau los ua kev tiv thaiv kab mob T hlwb . Cov no T hlwb ces tawm ntawm thymus , mus mus rau hauv cov hlab ntsha thiab nws thiaj li nrhiav tau lawv txoj kev mus rau cov qog nqaij hlav, mucosa-koom nrog lymphoid cov ntaub so ntswg los yog tus po. Kev ua haujlwm: tsim cov tshuaj tiv thaiv kab mob T lymphocytes.
Yooj yim li ntawd, thaum T cells tawm ntawm thymus lawv tuaj yeem mus rau?
Naiv T cells tawm ntawm thymus thiab nkag mus rau hauv cov ntshav. Yog lawv nyob twj ywm hauv cov ntshav, ces lawv yuav hla tus po. Naiv T cell ua tau kuj nkag mus rau cov qog nqaij hlav los ntawm kev hla siab endothelial venules (HEVs). Hauv cov 2˚ lymphoid kabmob, tsis paub meej T hlwb ntsib ntau txhiab tus APCs.
Ib tug kuj yuav nug, T lymphocytes ua haujlwm li cas? Pab T hlwb ua qhib Thaum lawv tau nthuav tawm nrog peptide antigens los ntawm MHC chav kawm II molecules, uas tau nthuav tawm nyob rau saum npoo ntawm antigen-presenting. hlwb (APCs). Ib zaug qhib , lawv faib sai thiab zais cov cytokines uas tswj lossis pab tiv thaiv kev tiv thaiv kab mob.
Qhov thib ob, T hlwb mus qhov twg tom qab paub tab?
Tiam ntawm T Cells Lymphoid progenitors uas tau tsim los ntawm hematopoietic qia hlwb nyob rau hauv cov pob txha pob txha tsiv mus rau thymus kom tiav lawv cov antigen-ywj siab kev loj hlob rau hauv kev ua haujlwm T hlwb.
Cov lymphocytes qhib qhov twg?
Kev ua kom lymphocyte tshwm sim thaum cov lymphocytes (B hlwb lossis T hlwb) tau tshwm sim los ntawm cov tshuaj tiv thaiv tshwj xeeb rau ntawm lawv lub xov tooj ntawm tes. Qhov no ua rau cov hlwb proliferate thiab sib txawv rau hauv tshwj xeeb effector cov lymphocytes.
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