Video: Dab tsi receptors ua antidepressants ua haujlwm?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Cov tshuaj Antidepressant ua rau kom rov tau txais cov tshuaj tshuaj serotonin (tianeptine), nce kev tso tawm ntawm tshuaj serotonin thiab norepinephrine (mirtazapine), ua ncaj qha rau tshuaj serotonin thiab melatonin receptors (agomelatine) lossis lwm yam cuam tshuam rau kev ua haujlwm sib txuas ntawm lub cev.
Tsis tas li kom paub yog, dab tsi receptors ua SSRIs ua haujlwm?
SSRIs ua haujlwm los ntawm kev nce qib extracellular ntawm cov neurotransmitter tshuaj serotonin los ntawm kev txwv nws cov reabsorption (reuptake) rau hauv presynaptic cell, nce qib ntawm tshuaj serotonin nyob rau hauv lub synaptic cleft muaj los khi rau postsynaptic receptor.
Tsis tas li ntawd, cov tshuaj tiv thaiv kev ntxhov siab ua haujlwm li cas ntawm neurotransmitters? SSRIs kho kev nyuaj siab los ntawm kev nce qib serotonin hauv lub hlwb. Serotonin yog ib tus neeg xa xov tshuaj ( cov neurotransmitters ) uas nqa cov cim nruab nrab ntawm lub hlwb paj hlwb (neurons). SSRIs thaiv cov reabsorption (reuptake) ntawm serotonin rau hauv neurons.
Hauv qhov no, dab tsi neurotransmitter cuam tshuam los ntawm antidepressants?
Qhov ntawd tau hais tias, ntau tus kws tshawb fawb ntseeg tias cov txiaj ntsig ntawm cov tshuaj tiv thaiv kev ntxhov siab yog los ntawm qhov lawv cuam tshuam rau qee lub hlwb circuits thiab cov tshuaj (hu ua neurotransmitters) uas dhau los ntawm ib lub paj hlwb mus rau lwm qhov hauv lub hlwb. Cov tshuaj no suav nrog tshuaj serotonin , dopamine , thiab norepinephrine.
Dab tsi yog cov txheej txheem tseem ceeb ntawm kev txiav txim ntawm cov tshuaj antidepressant?
Cov lub ntsiab hypothesis txog lub mechanism ntawm kev txiav txim ntawm cov tshuaj antidepressant yog monoaminergic thiab feem ntau cuam tshuam nrog ob lub paj hlwb, serotonin thiab noradrenaline. Txawm hais tias qhov kev lees paub kho tau zoo ntawm kev xaiv serotonin reuptake inhibitors (SSRIs), qee qhov tsis zoo tseem tshwm sim.
Pom zoo:
Dab tsi receptors ua milrinone ua haujlwm?
Milrinone txwv qhov kev ua ntawm phosphodiesterase hauv myocyte, ua rau nce intracellular cyclic adenosine monophosphate (cAMP) thiab calcium. Nws yog tus neeg sawv cev inotropic uas ua rau nqes los ntawm β-adrenergic receptor
Dab tsi receptors ua haujlwm naloxone?
Cov txheej txheem meej ntawm kev txiav txim ntawm opiate antagonist teebmeem ntawm naloxone tsis nkag siab tag nrho. Naloxone tau xav tias yuav ua raws li kev sib tw antagonist ntawm mc, κ, thiab σ opiate receptors hauv CNS; Nws yog xav tias cov tshuaj muaj qhov siab tshaj plaws affinity rau Μ receptor
Dab tsi yog qhov ua haujlwm ntawm cov hlab ntsha receptors?
Tus neeg txais kev nkag siab yog tus qauv uas cuam tshuam rau lub cev kev txhawb nqa hauv ib puag ncig, tsis hais sab hauv lossis sab nraud. Nws yog qhov kawg ntawm lub paj hlwb uas tau txais cov ntaub ntawv thiab ua cov txheej txheem ntawm kev tsim cov paj hlwb kom xa mus rau lub hlwb rau kev txhais lus thiab kev nkag siab
Dab tsi yog qhov tshwm sim ntawm tricyclic antidepressants?
Dab tsi yog cov teebmeem ntawm tricyclic antidepressants? pom qhov muag tsis pom kev, qhov ncauj qhuav, cem quav, qhov hnyav nce lossis poob, ntshav siab tsis txaus ntawm kev sawv, pob khaus, khaus khaus, thiab. nce lub plawv dhia
Lub luag haujlwm ntawm tus kws saib xyuas mob plawv tsis ua haujlwm yog dab tsi hauv kev saib xyuas cov neeg mob plawv tsis ua haujlwm?
Raws li ib feem ntawm pab pawg, tus kws kho mob lub plawv tsis ua haujlwm tau zoo muab rau muab kev pabcuam rau cov neeg mob thoob plaws txoj kev mob plawv tsis ua haujlwm thiab qhov no yuav tsum muaj kev koom tes ze nrog kws saib xyuas mob hauv thaj chaw tshwj xeeb tshwj xeeb xws li chav kho mob xwm txheej ceev thiab kev kho mob dav/ saib xyuas-ntawm-tus-neeg laus