Video: Alpha 1 thiab 2 receptors nyob qhov twg?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Alpha 1 receptors yog cov classic postsynaptic alpha receptors thiab muaj nyob rau ntawm vascular du nqaij. Lawv txiav txim siab ob qho kev tiv thaiv arteriolar thiab cov leeg ntshav, thiab yog li BP. Alpha 2 receptors tau pom ob leeg hauv lub hlwb thiab nyob ib puag ncig. Hauv lub paj hlwb, lawv hloov pauv kev nkag siab zoo.
Tsis tas li ntawd, alpha 2 adrenergic receptors nyob qhov twg?
Cov α2 - adrenergic receptor yog classic nyob ntawm vascular prejunctional davhlau ya nyob twg qhov nws txwv qhov tso tawm ntawm norepinephrine (noradrenaline) hauv daim ntawv ntawm cov lus tsis zoo.
Tom qab ntawd, lo lus nug yog, dab tsi yog qhov ua haujlwm ntawm alpha 2 receptors? Alpha 2 receptors nyob rau hauv lub hlwb qia thiab hauv ib puag ncig txwv tsis pub ua haujlwm zoo thiab yog li ua kom cov ntshav siab. Alpha 2 receptor agonists xws li clonidine los yog guanabenz txo qhov nruab nrab thiab peripheral sympathetic overflow thiab ntawm peripheral presynaptic receptors yuav txo tau peripheral neurotransmitter tso tawm.
Puas muaj alpha 1 receptors hauv plawv?
Alpha - 1 - cov tshuaj adrenergic receptors (ARs) yog G protein-coupled cov receptors qhib los ntawm catecholamines. Cov alpha -1A thiab alpha -1B subtypes yog qhia nyob rau hauv nas thiab tib neeg myocardium, whereas lub alpha -1D cov protein pom tsuas yog hauv cov hlab plawv.
Yuav ua li cas alpha 2 receptors ua rau vasoconstriction?
Ua kom muaj kev nkag siab zoo rau sab hauv cov hlab ntshav ua rau cov leeg sib zog ua haujlwm ( vasoconstriction ) txo qis caliber ntawm cov hlab ntsha lossis leeg. Alpha - 2 cov tshuaj adrenoceptors yog tam sim no ntawm presynaptic cov hlab ntsha dav dav thiab, thaum qhib, txwv tsis pub tso tawm norepinephrine.
Pom zoo:
Qhov chaw nyob ntawm thawj lub tsev kawm qib siab kho hniav nyob hauv ntiaj teb nyob qhov twg?
Dr. John M. Harris tau pib lub ntiaj teb thawj lub tsev kho hniav hauv Bainbridge, Ohio, thiab tau pab tsim kho hniav raws li kev noj qab haus huv. Nws qhib rau 21 Lub Ob Hlis 1828, thiab niaj hnub no yog tsev khaws puav pheej kho hniav. Thawj lub tsev kawm kho hniav, Baltimore College ntawm Kev Kho Hniav, tau qhib hauv Baltimore, Maryland, Asmeskas xyoo 1840
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