Yuav ua li cas tshem tawm gliclazide?

2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44

Gliclazide belongs rau chav kawm sulfonylurea ntawm insulin secretagogues, uas ua los ntawm kev txhawb nqa β hlwb ntawm tus txiav ua kom tso cov tshuaj insulin. Gliclazide yog metabolized ntau los ntawm daim siab; nws cov metabolites yog tso tawm hauv ob qho zis (60-70%) thiab quav (10-20%).

Ua qhov no saib, dab tsi yog qhov tshwm sim tshwm sim ntawm gliclazide?

Zoo li txhua yam tshuaj, gliclazide tuaj yeem ua rau cov kev mob tshwm sim , txawm hais tias tsis yog txhua tus tau txais lawv.

Cov kev mob tshwm sim

• mob plab los yog digestion.
• muaj mob (xws li xeev siab)
• mob (ntuav) lossis raws plab.
• cem quav.

Dab tsi yog cov txheej txheem ntawm kev ua ntawm gliclazide? Gliclazide stimulates insulin secretion los ntawm beta cell sulphonylurea receptor, thiab tejzaum nws los ntawm kev ncaj qha cov nyhuv ntawm kev thauj mus los ntawm calcium intracellular. Nws tshwj xeeb txhim kho qhov txawv txav thawj theem tso tawm insulin hauv hom 2 mob ntshav qab zib, thiab kuj tseem muaj cov nyhuv nyob rau theem ob.

Hauv qhov no, yuav ua li cas thiaj li tau txais gliclazide?

Gliclazide yog sai nqus nyob rau hauv txhua hom, nrog lub ncov plasma pom ntawm 1 thiab 6 teev. Ntau tshaj 90% ntawm gliclazide pom tsis hloov pauv hauv plasma. Kev tshem tawm yog qhov zoo sib xws hauv txhua hom tsiaj nrog 60 txog 70% ntawm cov tshuaj pom hauv cov zis thiab 10 txog 20% hauv quav.

Puas yog Gliclazide zoo ib yam li metformin?

Hauv qhov xaus, gliclazide tsis txhawb kev poob phaus hauv cov neeg rog rog tsis-insulin-vam khom cov neeg mob ntshav qab zib rau ib yam raws li metformin tab sis qhov sib txawv ntawm ob yam tshuaj yog me me. Gliclazide yog tus neeg sawv cev qhov ncauj hypoglycemic haum rau siv hauv cov neeg mob ntshav qab zib uas tsis tuaj yeem tswj tau los ntawm kev noj zaub mov ib leeg.