Video: Sglt2 diabetes yog dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
SGLT2 cov tshuaj tiv thaiv kab mob , tseem hu ua gliflozins, yog ib chav kawm ntawm cov tshuaj uas inhibit reabsorption ntawm qabzib nyob rau hauv lub raum thiab thiaj li txo cov ntshav qab zib. Lawv ua los ntawm inhibiting sodium-glucose thauj protein 2 ( SGLT2 ). SGLT2 cov tshuaj tiv thaiv kab mob yog siv rau hauv kev kho mob hom II ntshav qab zib mob ntshav qab zib mellitus (T2DM).
Ua li no, yam tshuaj twg yog sglt2 inhibitors?
- Canagliflozin (Invokana)
- Canagliflozin / Metformin (Invokamet)
- canagliflozin/metformin ncua kev tso tawm (Invokamet XR)
- dapagliflozin (Farxiga)
- dapagliflozin/metformin ncua kev tso tawm (Xigduo XR)
- dapagliflozin/saxagliptin (Qtern)
- empagliflozin (Jardiance)
- empagliflozin / linagliptin (Glyxambi)
Ib qho ntxiv, puas yog sglt2 inhibitors qhov ncauj? SGLT2 cov tshuaj tiv thaiv kab mob yog qhov ncauj tshuaj noj. Lawv muaj nyob rau hauv daim ntawv tshuaj. Piv txwv li, cov tshuaj no tuaj yeem ua ke nrog metformin. Kev sib xyaw ntawm cov tshuaj mob ntshav qab zib tuaj yeem pab koj ua kom koj cov ntshav qab zib nyob hauv cov hom phiaj.
Ntxiv mus, dab tsi yog qhov zoo tshaj plaws sglt2 inhibitor?
Tam sim no Selective SGLT2 Inhibitors Ntawm peb cov tshuaj FDA pom zoo, empagliflozin muaj qhov zoo tshaj plaws xaiv rau SGLT2 piv rau SGLT1, thaum canagliflozin yog qhov tsawg tshaj plaws xaiv (5).
Sglt2 inhibitors siv li cas?
Cov tshuaj no ua haujlwm los ntawm kev tiv thaiv cov piam thaj los ntawm kev nqus hauv lub raum. Yog li ntawd, lawv txo cov piam thaj hauv cov ntshav thiab ua rau nws ntws mus rau hauv cov zis. Thaum twg? Txoj kev kho mob yuav txawv rau txhua tus neeg, tab sis feem ntau SGLT2 cov tshuaj tiv thaiv kab mob noj ib zaug ib hnub ua ntej thawj pluas noj.
Pom zoo:
Dab tsi yog glycoprotein dab tsi yog ib qho ntawm kev siv glycoproteins?
Glycoproteins yog cov protein uas muaj cov oligosaccharide saw (glycans) covalently txuas nrog cov amino acid sab-saw. Glycoproteins kuj tseem yog ib qho tseem ceeb ua ke ntawm cov protein, uas lawv ua lub luag haujlwm hauv kev sib cuam tshuam ntawm tes -cell
Dab tsi yog cov khoom siv hauv lub cev zom zaub mov thiab lawv lub luag haujlwm yog dab tsi?
Cov khoom siv hauv lub cev zom zaub mov suav nrog cov hniav, tus nplaig, cov qog ua kua qaub, daim siab, lub zais zis, thiab txiav txiav. Txhawm rau ua tiav lub hom phiaj ntawm kev muab lub zog thiab khoom noj khoom haus rau lub cev, rau lub luag haujlwm tseem ceeb nyob hauv cov txheej txheem zom zaub mov: nqos. Kev zais
Dab tsi yog qhov kev nkag siab tsis tu ncua thiab dab tsi yog qhov loj me me qhov ntev xim tsis tu ncua zoo li qub)?
Kev nkag siab tsis tu ncua, tseem hu ua qhov tsis sib xws, lossis qhov tshwm sim tsis tu ncua, kev nyiam tsiaj thiab tib neeg kom pom cov khoom paub zoo li muaj tus qauv zoo, qhov loj me, xim, lossis qhov chaw tsis hais txog kev hloov pauv ntawm lub kaum sab xis ntawm kev xav, nrug deb, lossis teeb pom kev zoo
Lub cev tseem ceeb ntawm lub plab zom mov yog dab tsi thiab lawv lub luag haujlwm yog dab tsi?
Cov khoom siv hauv lub cev zom zaub mov suav nrog cov hniav, tus nplaig, cov qog ua kua qaub, daim siab, lub zais zis, thiab txiav txiav. Txhawm rau ua tiav lub hom phiaj ntawm kev muab lub zog thiab khoom noj khoom haus rau lub cev, rau lub luag haujlwm tseem ceeb nyob hauv cov txheej txheem zom zaub mov: nqos. Kev zais. Sib tov thiab txav mus los. Digestion. Kev nqus. Kev tshem tawm
Dab tsi yog cov npe tshuaj rau sglt2 inhibitors?
Cov npe tshuaj thiab cov npe ntawm SGLT2 inhibitors thiab cov khoom sib xyaw ua ke uas muaj SGLT2 inhibitors suav nrog: canagliflozin (Invokana) canagliflozin / metformin (Invokamet) canagliflozin / metformin ncua kev tso tawm (Invokamet XR) dapagliflozin (Farxiga) dapagliflozin (X) tso tawm