Video: Dab tsi yog Bence Jones protein nyob rau hauv cov zis?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
A Bence Jones cov protein yog monoclonal globulin protein ntau lossis immunoglobulin teeb pom muaj nyob hauv tso zis , nrog lub cev hnyav ntawm 22-24 kDa. Kev kuaj pom ntawm Bence Jones cov protein Tej zaum yuav qhia tau tias muaj ntau yam myeloma lossis Waldenström's macroglobulinemia. Bence Jones proteins muaj nyob rau hauv 2/3 ntawm ntau tus neeg mob myeloma.
Ib sab ntawm qhov no, nws txhais tau li cas yog tias kuv muaj Bence Jones cov protein hauv kuv cov zis?
Bence - Jones cov protein feem ntau tsis nyob hauv tso zis . Cov nyob ntawm Bence - Jones proteins nyob rau hauv tso zis tuaj yeem yog ib qho cim ntawm ntau yam myeloma lossis lwm yam mob tsis tshua muaj hu ua Waldenstrom macroglobulinemia. Qhov no protein ntau tuaj yeem nyob hauv koj cov zis yog tias koj muaj monoclonal gammopathy ntawm qhov tsis tseem ceeb (MGUS).
Tsis tas li ntawd, dab tsi yog thawj cov cim qhia ntawm ntau yam myeloma? Cov cim qhia ceeb toom ntxov ntawm ntau yam myeloma
- Mob pob txha (feem ntau nyob nraub qaum lossis tav)
- Unexplained pob txha fractures (feem ntau nyob rau hauv tus txha nqaj qaum)
- Qaug zog, hnov qaug zog.
- Cov kab mob rov tshwm sim, ua npaws.
- Ua tsis taus pa.
- Poob poob.
- Ntshai.
- Cem quav.
Kuj tseem paub, qhov kuaj zis BJP yog dab tsi?
Cov Bence Jones cov protein ( BJP ) xeem ntsuas qib ntawm BJP hauv koj tso zis . Cov proteins no tsis muaj nyob hauv kev noj qab haus huv tso zis kuaj thiab feem ntau yog ib qho cim ntawm ntau yam myeloma. Ntau myeloma yog hom mob qog nqaij hlav hauv pob txha uas feem ntau tshwm sim hauv cov neeg laus dua 60 xyoo.
Dab tsi yog monoclonal protein nyob rau hauv cov zis?
Ntau myeloma thiab MGUS yog ob qho laj thawj uas tshwm sim monoclonal protein ntau hauv serum or tso zis . Feem ntau lees txais kev kuaj mob triad rau ntau yam myeloma suav nrog ib qho tseem ceeb paraprotein hauv cov ntshav los yog tso zis , ntau dua 10% txog 15% cov ntshav ntshav hauv cov leeg pob txha, thiab muaj cov kab mob pob txha.
Pom zoo:
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