Video: Vim li cas Fosphenytoin nyiam dua phenytoin?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Fosphenytoin yog ib txoj cai tswj hwm ntawm niam txiv phenytoin , siv hauv kev kho cov neeg mob uas qaug dab peg. Qhov zoo ntawm fosphenytoin tshaj phenytoin suav nrog kev tswj hwm cov hlab ntsha sai dua, tsis tas yuav muaj cov lim dej hauv cov hlab ntsha, thiab txo qis rau cov ntaub so ntswg hauv zos thiab lub plawv toxicity.
Ib sab ntawm qhov no, qhov sib txawv loj ntawm Fosphenytoin thiab phenytoin yog dab tsi?
** Qhov sib txawv ntawm fosphenytoin thiab phenytoin feem ntau yog vim fosphenytoin ua dej ntau soluble. Fosphenytoin > tuaj yeem ua rau ntawm qhov nrawm dua (20 mg / kg phenytoin Qhov sib npaug (PE's) thauj khoom ntawm tus nqi ntawm 100 mus rau 150 mg ntawm PE's / feeb) vim nws qhov kev nyab xeeb dua / cuam tshuam qhov profile.
Yog vim li cas thiamine muab nyob rau hauv cov xwm txheej epilepticus? Thiamine (100 mg) yuav tsum yog muab nrog rau cov piam thaj, vim tias qabzib infusion ua rau muaj kev pheej hmoo ntawm Wernicke's encephalopathy hauv cov neeg mob raug mob. Tom qab kev tswj hwm cov pa oxygen, cov roj ntshav yuav tsum tau txiav txim siab kom muaj cov pa oxygen txaus.
Yog li ntawd, koj yuav hloov Fosphenytoin rau phenytoin li cas?
Koob tshuaj hloov dua siab tshiab los ntawm fosphenytoin rau phenytoin yog 1: 1 piv, nrog 1mg PE fosphenytoin 1 mg = np phenytoin . Pediatrics: Loading koob tshuaj: 18 txog 20 mg/kg IV Kev saib xyuas koob tshuaj: 2 txog 3 mg/kg/IV koob ob zaug ib hnub (4 txog 6 mg/kg/hnub), txawm hais tias yuav tsum tau txhaj tshuaj ntau dua raws qib.
Fosphenytoin puas tuaj yeem muab IV thawb?
Fosphenytoin yuav tsum tau 8 mus rau 15 feeb rau nws yuav tsum tau hydrolyzed rau phenytoin. Fosphenytoin tej zaum yuav ua thawj coj intramuscularly (IM) lossis IV , piv rau phenytoin, uas yog tswj IV thiab hais lus (PO).
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