Video: Vim li cas monoclonal antibodies tseem ceeb?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Monoclonal antibodies (mAb) tseem ceeb reagents siv nyob rau hauv kev tshawb fawb biomedical, kuaj mob, thiab kho cov kab mob xws li kab mob thiab mob qog noj ntshav. Cov no tshuaj tiv thaiv yog tsim los ntawm cov kab ntawm tes los yog clones tau los ntawm cov tsiaj uas tau txhaj tshuaj tiv thaiv kab mob uas yog qhov kev kawm.
Ntxiv mus, vim li cas cov tshuaj tiv thaiv kab mob monoclonal muaj txiaj ntsig?
Kev siv ntawm monoclonal tshuaj tiv thaiv los kho cov kab mob hu ua immunotherapy therapy vim txhua hom monoclonal tshuaj tiv thaiv yuav tsom ib qho antigen tshwj xeeb hauv lub cev. Siv rau monoclonal tshuaj tiv thaiv suav nrog: Cancer. Rheumatoid mob caj dab.
Ib yam li ntawd, cov tshuaj tiv thaiv siv rau dab tsi? Ib tshuaj tiv thaiv (Ab), tseem hu ua immunoglobulin (Ig), yog ib qho loj, Y-zoo li cov protein uas tsim los ntawm cov ntshav plasma uas yog siv los ntawm lub cev tiv thaiv kab mob kom tshem tawm cov kab mob xws li kab mob thiab kab mob.
Thiab cov lus nug yog, dab tsi yog qhov zoo ntawm kev siv cov tshuaj tiv thaiv kab mob monoclonal los kho mob qog noj ntshav?
Monoclonal antibodies yog lub chaw soj nstuam tsim tawm molecules engineered los ua kev hloov tshuaj tiv thaiv uas tuaj yeem rov kho dua, txhim kho lossis ua raws li lub cev tiv thaiv kab mob kev tawm tsam mob qog noj ntshav hlwb. Lawv tau tsim los khi rau cov antigens uas feem ntau muaj ntau ntau ntawm qhov chaw mob qog noj ntshav cov hlwb tshaj cov hlwb noj qab haus huv.
Koj txhais li cas los ntawm monoclonal antibodies?
Monoclonal antibodies (mAb or moAb) are tshuaj tiv thaiv uas yog tsim los ntawm tib lub cev tiv thaiv kab mob uas yog tag nrho cov clones ntawm cov niam txiv tshwj xeeb ntawm tes. Hauv kev sib piv, polyclonal tshuaj tiv thaiv khi rau ntau yam epitopes thiab feem ntau yog tsim los ntawm ntau qhov sib txawv ntawm tes ( tshuaj tiv thaiv secreting tiv thaiv cell) kab.
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