Video: Neurofibrillary tangles ua rau dementia li cas?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Neurofibrillary tangles yog Qhov txawv txav ntawm cov protein hu ua tau uas sau hauv cov neurons. Hauv Alzheimer tus kab mob kab mob, txawm li cas los xij, hloov pauv tshuaj lom neeg ua tau kom tshem tawm ntawm microtubules thiab lo rau lwm cov tau molecules, tsim cov xov uas nws thiaj li koom ua ke tangles hauv cov neurons.
Yog li ntawd, neurofibrillary tangles ua li cas?
Neurofibrillary tangles yog insoluble twisted fibers pom nyob rau hauv lub hlwb lub hlwb. Cov no tangles Muaj feem ntau ntawm cov protein hu ua tau, uas yog ib feem ntawm cov qauv hu ua microtubule. Lub microtubule pab thauj cov as-ham thiab lwm yam tseem ceeb ntawm ib feem ntawm cov paj hlwb mus rau lwm qhov.
Kuj Paub, puas neurofibrillary tangles tshwm sim nyob rau hauv tag nrho cov cheeb tsam ntawm lub hlwb? Alzheimer's feem ntau cuam tshuam nrog ob hom kab mob thoob plaws hauv lub hlwb cortex : amyloid plaques, uas muaj nyob nruab nrab ntawm cov neurons, thiab neurofibrillary tangles , uas muaj nyob rau hauv lawv. Beta-amyloid yog muab los ntawm cov protein ntau molecule uas muaj nyob rau hauv daim nyias nyias nyob ib puag ncig cov paj hlwb noj qab haus huv.
Tsis tas li ntawd, dab tsi yog qhov laj thawj tseem ceeb ntawm dementia?
Qhov thib ob loj degenerative ua rau dementia yog Alzheimer tus kab mob kab mob (kev loj hlob ntawm cov paj hlwb tsis paub txog qhov ua rau) thiab vascular dementia (piv txwv li poob ntawm lub hlwb ua haujlwm vim muaj cov kab mob me me).
Qhov mob twg yog txuam nrog neurofibrillary tangles thiab kev nco ploj?
Tom qab nws tuag, nws tau tshuaj xyuas nws lub hlwb thiab pom ntau cov kab mob txawv txav (tam sim no hu ua amyloid plaques) thiab tangled bundles ntawm fibers (tam sim no hu ua neurofibrillary , los yog tau , tangles ). Cov plaques no thiab tangles nyob rau hauv lub hlwb tseem suav tias yog qee yam ntawm cov yam ntxwv tseem ceeb ntawm Alzheimer's kab mob.
Pom zoo:
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