Video: Puas yog fluoroquinolones concentration lossis lub sijhawm nyob ntawm?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Ntxhuav
| Sijhawm - Nyob ntawm tus neeg (nrog tsawg lossis tsis muaj PAE) | Nco ntsoov - Nyob ntawm tus neeg (nrog PAE) |
|---|---|
| Beta-lactams Vancomycin | Aminoglycosides Daptomycin Fluoroquinolones Metronidazole Azithromycin Ketolides |
Thiaj li, puas yog aminoglycosides lub sijhawm nyob lossis qhov siab?
Pawg thib ob suav nrog cov tshuaj uas nthuav tawm siab - nyob ntawm Cov kab mob bactericidal thiab ntev PAEs (piv txwv li, cov aminoglycosides , fluoroquinolones, daptomycin, colistin, metronidazole, tejzaum nws yog azalide azithromycin, thiab ketolides).
Tsis tas li, puas yog lub sijhawm tetracyclines lossis qhov xav tau? Pharmacodynamics: Tetracyclines tsim ib qho kev sib txuas ntawm siab thiab sij hawm - nyob ntawm tua (AUC: MIC ratio).
Ua li no, yam tshuaj tua kab mob twg yog lub sijhawm lossis nyob ntawm qhov xav tau?
Hom III tshuaj tua kab mob (vancomycin, tetracyclines, azithromycin, thiab dalfopristin-quinupristin ua ke) muaj cov khoom sib xyaw, sij hawm - nyob ntawm tua thiab nruab nrab cov teebmeem tsis tu ncua. Cov txheej txheem kev noj tshuaj zoo tshaj plaws rau cov no tshuaj tua kab mob ua kom cov tshuaj tau txais ntau tshaj plaws.
Puas yog penicillins lub sij hawm lossis concentration nyob ntawm?
Sijhawm - Nyob ntawm tus neeg Tua: Piv txwv, qee yam tshuaj tua kab mob, xws li beta-lactams ( penicillins , cephalosporins, carbapenems, monobactams), clindamycin, macrolides (erythromycin, clarithromycin), oxazolidinones (linezolid), tuaj yeem ua haujlwm tau zoo vim tias muaj nyiaj ntau sij hawm cov tshuaj tua kab mob khi rau cov kab mob.
Pom zoo:
Lub sijhawm rau cov ntaub so ntswg dawb nyob ib ncig ntawm lub qhov muag thiab tsim lub hauv paus txheej txheem ntawm lub ntiaj teb yog dab tsi?
Qhov muag. Cov ntaub so ntswg dawb nyob ib ncig ntawm lub qhov muag thiab ua lub hauv paus tseem ceeb ntawm lub ntiaj teb yog. iris, lub cev ciliary, choroid. Cov qauv ntawm cov kab mob uveal, lossis uvea, yog. dej lom zem
Thaum ob lossis ntau tus neeg mob tau teem sijhawm teem sijhawm tib lub sijhawm nws paub zoo li?
MOS 130 Chav 4 Kev Kawm Ntawv Kev Kho Mob Qhia Ntawv Kho Mob Lub Chaw Haujlwm Txais Tos (Sib Raug Zoo) AB cov neeg mob taug kev uas tuaj rau tom chaw haujlwm yam tsis tau teem sijhawm yoj teem sijhawm cov txheej txheem ntawm kev teem sijhawm sib ntsib uas ntau tus neeg mob tau muab sijhawm tib lub sijhawm thiab pom nyob hauv xaj kom lawv tuaj txog
Dab tsi yog lub sijhawm rau pob txha fusion ntawm ob lossis ntau lub vertebrae uas tsim cov phab ntsa tom qab ntawm lub plab hlaub hauv tib neeg?
Lub sacrum (/ˈsækr? M/lossis/?se? Kr? M/; plural: sacra lossis sacrums), hauv tib neeg lub cev, yog cov pob txha loj, peb tog ntawm lub hauv paus ntawm tus txha nraub qaum uas tsim los ntawm kev sib xyaw ntawm sacral vertebrae S1– S5 ntawm hnub nyoog 18 thiab 30 xyoos. Lub sacrum nyob rau sab sauv, sab nraub qaum ntawm lub plab kab noj hniav, nruab nrab ntawm ob lub tis ntawm lub plab mog
Nyob rau hauv dab tsi lub cev kua compartment yog ib txwm muaj siab concentration ntawm poov tshuaj?
Hauv cov kua dej hauv lub cev twg ib txwm muaj qhov siab ntawm cov poov tshuaj? ICF muaj ntau cov poov tshuaj thiab cov sodium tsawg. ECF thiab interstitial kua muaj cov sodium ntau thiab cov poov tshuaj tsawg
Puas yog linezolid lub sijhawm vam khom lossis nyob ntawm qhov xav tau?
Cov tshuaj tua kab mob raws sij hawm. Sab laug: Lub sijhawm tiv thaiv cov tshuaj tua kab mob (beta-lactams, suav nrog penicillins thiab penems, glycopeptides, linezolid, macrolides, thiab lwm yam). Lub sijhawm uas cov tshuaj nyob qis dua MIC (T> MIC) yog PK-PD qhov ntsuas cuam tshuam nrog kev ua tau zoo