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Video: TPA yog dab tsi thiab nws ua haujlwm li cas?
![Video: TPA yog dab tsi thiab nws ua haujlwm li cas? Video: TPA yog dab tsi thiab nws ua haujlwm li cas?](https://i.ytimg.com/vi/_9-40PVJzO0/hqdefault.jpg)
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
TPA yog cov protein uas tshwm sim ib txwm pom nyob rau ntawm cov qog endothelial, cov cell uas kab cov hlab ntshav. Nws ua rau kev hloov pauv ntawm plasminogen rau plasmin, ib qho enzyme lub luag haujlwm rau kev tawg ntawm cov ntshav txhaws. 2? TPA ua haujlwm los ntawm kev tiv thaiv kev txhaws ntawm cov ntshav txhaws uas cuam tshuam cov ntshav ntws hauv lub hlwb.
Ntxiv mus, tPA yog dab tsi thiab thaum twg nws siv?
Kev siv tshuaj kho mob. tPA tau siv rau qee kis ntawm cov kab mob uas ua rau pom ntshav txhaws , xws li pulmonary embolism, myocardial infarction, thiab mob stroke , hauv kev kho mob hu ua thrombolysis. Feem ntau siv rau ischemic mob stroke.
Ib yam nkaus, cov txiaj ntsig ntawm tPA yog dab tsi? Lwm yam tseem ceeb cov kev mob tshwm sim suav nrog: xeev siab ntuav.
Lwm yam kev mob tshwm sim hnyav muaj xws li:
- Pulmonary embolism.
- Cov roj (cholesterol) embolism.
- Lub plawv dhia txawv txav.
- Ua xua.
- Rov tsim dua tshiab ntawm qhov tob DVT venous thrombi thaum kho mob hnyav mob ntsws loj heev.
- Angioedema.
Xav txog qhov no, yog tPA txaus ntshai?
Ib qho tshuaj tiv thaiv kab mob hu ua tPA, lossis cov nqaij plasminogen activator, tau ua rau xob laim vim nws tau pom zoo thawj zaug hauv Tebchaws Meskas xyoo 1996. Txawm hais tias kev tshawb fawb tau pom tias cov tshuaj tuaj yeem txo qis lub hlwb kev puas tsuaj los ntawm kev mob stroke, nws kuj tuaj yeem ua rau muaj peev xwm ua rau tuag taus ntawm cerebral los ntshav.
Lub tswv yim ntawm kev ua ntawm tPA yog dab tsi?
Mechanism of Action tPA yog thrombolytic (piv txwv li, nws tawg ua ntshav khov) tsim los ntawm kev sib sau ua ke cov platelets qhib rau hauv fibrin meshes los ntawm kev ua kom plasminogen. Tshwj xeeb tshaj yog, nws tshem tawm zymogen plasminogen ntawm nws Arg561-Val562 peptide bond los tsim cov serine protease, plasmin.
Pom zoo:
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