Koj tswj hwm Argatroban li cas?
Koj tswj hwm Argatroban li cas?

Video: Koj tswj hwm Argatroban li cas?

Video: Koj tswj hwm Argatroban li cas?
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Thawj koob tshuaj

Pib ib qho infusion ntawm Argatroban Txhaj tshuaj ntawm 25 mcg/kg/min thiab tswj hwm ib qho bolus ntawm 350 mcg / kg los ntawm txoj kab bore loj tshaj li 3 mus rau 5 feeb (saib Table 2). Tshawb xyuas lub sij hawm ua kom muaj ntshav khov (ACT) 5 mus rau 10 feeb tom qab txhaj tshuaj bolus tiav.

Ua qhov no hauv kev txiav txim siab, puas yog Argatroban qhov ncauj?

Argatroban tau muab tso rau hauv cov hlab ntshav thiab cov ntshav plasma cov tshuaj nkag mus rau lub xeev ruaj khov hauv 1-3 teev. Argatroban yog metabolized hauv daim siab thiab muaj ib nrab neej li ntawm 50 feeb.

Argatroban.

Cov ntaub ntawv kho mob
Kev khi cov protein 54%
Metabolism mob siab
Tshem tawm ib nrab-lub neej 39i51 nqi
Cov cim qhia

Tsis tas li ntawd, thaum twg kuv tuaj yeem pib Argatroban tom qab heparin? Thaum INR yog ntawm lub hom phiaj, tsum tsis txhob muab cov tshuaj anticoagulant rau niam txiv. argatroban /bivalirudin infusion Nres heparin Pib infusion tam sim ntawd tom qab heparin infusion nres. heparin infusion Yog tias HIT tau raug txiav tawm, nres bivalirudin Pib heparin Txoj kev lis ntshav tam sim ntawd tom qab bivalirudin infusion nres.

Ib qho ntxiv, koj yuav saib xyuas Argatroban li cas?

Argatroban yog saib xyuas siv lub sijhawm ua haujlwm ib nrab thromboplastin (aPTT). Lub hom phiaj aPTT hauv vib nas this tau txhais ntawm UWMC/HMC li 60-80 vib nas this. Xwb, nws tuaj yeem ua tau saib xyuas Nrog rau qhov kev ntsuam xyuas ncaj qha thrombin inhibitor muaj nyob ntawm UWMC / HMC.

Vim li cas argatroban siv hauv kev ntaus?

Argatroban , cov khoom siv hluavtaws ncaj qha thrombin inhibitor, tau qhia rau kev kho mob thiab tiv thaiv kev tiv thaiv ntawm thrombosis hauv cov neeg mob HIT , suav nrog cov uas tab tom cuam tshuam kev phais plawv.

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