Video: Rifaximin kho tus mob hepatic encephalopathy li cas?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Tus qauv ntawm kev saib xyuas rau kev kho mob ntawm tus kab mob HE yog lactulose, uas tsis tuaj yeem nqus tau cov disaccharide uas tau xav kom tshem tawm thiab txo qis kev nqus ntawm ammonia. Rifaximin yog ib qho tshuaj tua kab mob tsis zoo uas xav tias yuav txo qis ammonia los ntawm kev tshem tawm cov kab mob ammonia-ua rau cov kab mob colonic.
Kuj nug, hom kev ua ntawm rifaximin yog dab tsi?
Mechanism Of Action Rifaximin yog ib qho khoom siv hluavtaws ib nrab ntawm rifampin thiab ua los ntawm kev khi rau beta-subunit ntawm cov kab mob DNA-nyob RNA polymerase thaiv ib qib ntawm cov ntawv sau tseg. Qhov no ua rau inhibition ntawm cov kab mob protein synthesis thiab yog li inhibits kev loj hlob ntawm cov kab mob.
Ib tug kuj yuav nug, yuav muab tshuaj dab tsi los txo cov ammonia? Lactulose
Ib yam li ntawd, yam tshuaj twg feem ntau siv hauv kev kho mob hepatic encephalopathy?
Ob yam tshuaj feem ntau siv los kho tus mob HE yog lactulose , cov khoom qab zib los yog txiv neej ua qab zib, thiab qee yam tshuaj tua kab mob. Qee zaum lactulose thiab tshuaj tua kab mob yog siv ua ke.
Yuav ua li cas lactulose pab nyob rau hauv hepatic encephalopathy?
Lactulose zoo li cuam tshuam kev tsim cov hnyuv ammonia los ntawm tus lej ntawm cov txheej txheem. Colonic metabolism ntawm lactulose lactic acid ua rau acidification ntawm lub plab lumen. Qhov no txhawb kev hloov pauv ntawm ammonium (NH4) mus rau ammonia (NH3) thiab kev hla ntawm ammonia los ntawm cov ntaub so ntswg mus rau hauv lumen.
Pom zoo:
Lub neej kev cia siab ntawm tus neeg mob hepatic encephalopathy yog dab tsi?
Kev Kho Mob Hepatic encephalopathy Kev txhawb nqa kev saib xyuas, kho mob, lactulose, hloov pauv daim siab Kev kwv yees Lub neej nruab nrab kwv yees li ib xyoos hauv cov neeg muaj kab mob hnyav Zuj Zus Muaj feem cuam tshuam> 40% nrog mob qog noj ntshav
Ntev npaum li cas ib tus neeg nyob nrog tus mob hepatic encephalopathy?
Qhov tshwm sim ntawm tus mob encephalopathy hnyav txaus los coj mus pw hauv tsev kho mob yog cuam tshuam nrog qhov muaj peev xwm muaj sia nyob ntawm 42% ntawm 1 xyoos ntawm kev taug qab thiab 23% ntawm 3 xyoos. Kwv yees li 30% ntawm cov neeg mob tuag thaum kawg ntawm daim siab mob ua rau muaj tus mob encephalopathy, nce mus rau qhov tsis nco qab
Koj yuav ntsuas tus mob hepatic encephalopathy li cas?
Cov tsos mob: Tus cwj pwm lossis tus cwj pwm hloov pauv
Yuav kho tus mob hepatic encephalopathy li cas nrog cov as-ham?
Lub hom phiaj tseem ceeb rau tus neeg mob uas muaj lub siab tsis ua haujlwm kawg yog kom zam dhau los ntawm txhua txoj kev ua kom poob phaus thiab txhawb nqa cov khoom noj uas muaj cov as-ham. Kev noj zaub mov zoo ntawm 35-40 kcal/kg/hnub tau pom zoo. Kev noj zaub mov tsis muaj protein ntau yuav tsum tau zam thiab noj cov protein kom tsawg ntawm 1.2-1.5 g / kg / hnub
Thaum tus kws kho mob tau tso cai tso cai ntau npaum li cas yuav tsum muaj kev sib ntsib tim ntsej tim muag tshwm sim ntawm tus kws kho mob thiab cov kws kho mob qib siab uas tau sau npe rau tus nais maum?
Txawm li cas los xij, yog tias APRN lossis PA tau nyob hauv daim ntawv pom zoo tso cai nrog kws saib xyuas kws kho mob tsawg kawg tsib ntawm xya xyoo dhau los, cov rooj sib tham tim ntsej tim muag yuav tsum tshwm sim tsawg kawg ib hlis txog rau thawj hnub ntawm hnub uas tau pom zoo kos npe