Video: Sm RNP antibody kuaj ntshav yog dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Extractable Nuclear Antigen Antibodies
Yog li, cov vaj huam sib luag uas ntsuas rau cov ENAs tshwj xeeb tuaj yeem pab tau rau hauv kev ntsuam xyuas ntawm SARDs. Sm/RNP (U1 RNP) yog ENA cuam tshuam nrog MCTD. Tiv thaiv -Sm/RNP cov tshuaj tiv thaiv yog tus yam ntxwv ntawm MCTD thiab pom muaj nyob hauv cov neeg mob feem coob.
Ib yam li ntawd, nws tau nug, qhov zoo ntawm SM RNP antibody txhais li cas?
Txawm hais tias muaj feem cuam tshuam nrog cov kab mob sib txuas, RNP cov tshuaj tiv thaiv tsis suav tias yog "tus cim" rau ib qho kab mob tshwj xeeb tshwj tsis yog hauv cov xwm txheej hauv qab no: thaum pom nyob rau hauv kev sib cais (piv txwv li, dsDNA tshuaj tiv thaiv thiab Sm cov tshuaj tiv thaiv tsis ntes tau), a zoo tshwm sim rau RNP cov tshuaj tiv thaiv yog zoo ib yam nrog cov
Ib yam nkaus, dab tsi yog suav tias yog RNP siab? Lub npe ntawm ≧ 1: 160 yog txiav txim siab zoo . Zoo RNP ab cov txiaj ntsig (> 1 antibody index (AI)) tau pom tias yog qis (1-3 AI) lossis siab (> 3 AI).
Hauv qhov no, dab tsi yog qib RNP cov tshuaj tiv thaiv ib txwm muaj?
Qhov siab tiv thaiv RNP qib yog tsim nyog rau kev kuaj mob ntawm MCTD; nws muaj qhov rhiab heev ntawm 95% -100%, tshwj xeeb tshaj yog tias nws pom nyob rau hauv siab titers (piv txwv li, 1: 1, 000, 000) thiab nyob rau hauv kev sib cais (xws li tsis muaj lwm yam extractable nuclear antigens xws li anti-ob stranded DNA). Titers qis tau cuam tshuam nrog lwm cov kab mob rheumatologic.
Kev kuaj ntshav tiv thaiv SM yog dab tsi?
Tiv thaiv - Sm ( tiv thaiv -Smith, muaj npe rau thawj tus neeg mob paub tias muaj cov tshuaj tiv thaiv kab mob no) cuam tshuam nrog tus qauv ANA me me thiab yog cov tshuaj tiv thaiv pom hauv cov neeg mob feem ntau uas tsis muaj tiv thaiv -dDNA. Qee tus neeg mob muaj ob qho tib si tiv thaiv -dsDNA thiab tiv thaiv - Sm . Tiv thaiv - Sm antibody khi rau cov protein uas txuas nrog DNA.
Pom zoo:
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Superior vena cava
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