Video: TNF inhibitors ua dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
TNF blockers suppress lub cev tiv thaiv kab mob los ntawm kev thaiv cov haujlwm ntawm TNF , ib yam khoom hauv lub cev uas tuaj yeem ua rau mob thiab ua rau lub cev tsis muaj zog, xws li Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis thiab plaque psoriasis.
Ib yam nkaus, ua li cas TNF inhibitors ua haujlwm?
TNF inhibitors yog cov tshuaj tiv thaiv tau tsim nyob rau hauv ib chav kuaj los ntawm tib neeg lossis tsiaj cov ntaub so ntswg. (Koj lub cev ua cov tshuaj tiv thaiv kab mob rau tiv thaiv kab mob.) Thaum lawv muab tso rau hauv koj cov ntshav, lawv ua rau muaj kev cuam tshuam hauv koj lub cev tiv thaiv kab mob uas thaiv qhov mob. Koj lub cev tiv thaiv kab mob ua rau cov tshuaj hu ua qog necrosis factor ( TNF ).
Tsis tas li ntawd, yog Methotrexate yog TNF inhibitor? Methotrexate feem ntau txwv tsis pub qhib thiab nthuav tawm ntawm lymphocytes. TNF inhibitors inhibit monocytes thiab myeloid dendritic hlwb, thiab tocilizumab muaj kev ua haujlwm dav dua thiab raug coj tawm tsam ob leeg lymphoid thiab myeloid compartment.
Ua qhov no hauv kev txiav txim siab, puas yog TNF blockers nyab xeeb?
TNF blockers , uas tau txiav txim siab txog biologic DMARDs, suav nrog Enbrel (etanercept), Humira (adalimumab), Remicade (infliximab), Simponi (golimumab), thiab Cimzia (certolizumab pegol). Lawv muaj qhov txiaj ntsig zoo heev / kev pheej hmoo. Hauv lwm lo lus, thaum muaj kev phom sij loj tuaj yeem tshwm sim, lawv tsis zoo ib yam.
Cov tshuaj tiv thaiv qog necrosis yog dab tsi?
Piv txwv. Inhibition ntawm TNF cov teebmeem tuaj yeem ua tiav nrog cov tshuaj tiv thaiv kab mob monoclonal xws li infliximab (Remicade), adalimumab (Humira), certolizumab pegol (Cimzia), thiab golimumab (Simponi), lossis nrog cov kis tau txais cov protein sib xyaw xws li etanercept (Enbrel).
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