Dab tsi yog qhov piv txwv ntawm endogenous antigen?

2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44

Endogenous antigens cov yog cov proteins pom nyob rau hauv cytosol ntawm tib neeg lub hlwb. Piv txwv ntawm endogenous antigens suav nrog: cov protein uas tau khiav mus rau cytosol los ntawm phagosome ntawm phagocytes xws li antigen -nthuav tawm cov cell; qog antigens tsim los ntawm cov qog nqaij hlav cancer; thiab.

Tsis tas li ntawd, dab tsi yog qhov endogenous antigen?

Endogenous antigens cov yog cov teeb liab tsim nyob rau hauv koj lub cev cov hlwb (tau kis los ntawm tus kab mob) uas pib lub cev tiv thaiv kab mob. Lawv ceeb toom cytotoxic T hlwb tias lub cev cell kis tau tus kab mob, xws li mob khaub thuas, lossis tau ua mob qog noj ntshav.

Tsis tas li, dab tsi yog endogenous thiab exogenous antigens? Ib antigen yog ib qho molecule uas pib tsim cov tshuaj tiv thaiv kab mob thiab ua rau muaj kev tiv thaiv kab mob. Antigens feem ntau yog cov protein, peptides, lossis polysaccharides. Antigens raug cais raws li exogenous (nkag los sab nraud) endogenous (tsim nyob rau hauv lub hlwb), autoantigen, qog antigen , los yog ib haiv neeg antigen.

Ib yam nkaus, tib neeg nug, dab tsi yog qee qhov piv txwv ntawm antigens?

Txawv teb chaws antigens los ntawm sab nraud lub cev. Piv txwv suav nrog ib feem ntawm lossis cov tshuaj tsim los ntawm cov kab mob lossis kab mob me me (xws li kab mob thiab protozoa), nrog rau cov tshuaj nyob rau hauv nab venom, qee cov proteins hauv cov khoom noj, thiab cov khoom ntawm cov ntshav thiab cov qe ntshav liab los ntawm lwm tus neeg.

Dab tsi yog 3 hom antigens?

Muaj peb hom antigen nthuav tawm cov hlwb hauv lub cev: macrophages, dendritic cells thiab В cells

• Macrophages: Macrophages feem ntau pom muaj nyob hauv lub xeev so.
• Dendritic Cells: Cov hlwb no yog tus cwj pwm los ntawm cov txheej txheem cytoplasmic ntev.
• B-hlwb: