![Puas yog Metformin yog DPP 4 inhibitor? Puas yog Metformin yog DPP 4 inhibitor?](https://i.answers-medical.com/preview/medical-health/13880091-is-metformin-a-dpp-4-inhibitor-j.webp)
Video: Puas yog Metformin yog DPP 4 inhibitor?
![Video: Puas yog Metformin yog DPP 4 inhibitor? Video: Puas yog Metformin yog DPP 4 inhibitor?](https://i.ytimg.com/vi/1YLJWUFpZ1I/hqdefault.jpg)
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Cov txheej txheem tseem ceeb nce qib GLP-1 los ntawm metformin tshuaj tseem yuav tsum tau tsim thaum kawg; nws tau raug qhia tias yog tshwm sim los ntawm txwv tsis pub ntawm DPP - 4 (Lindsay li al 2005; Mannucci li al 2001), txawm hais tias tseem muaj kev tshawb pom qhov ntawd metformin tshuaj tsis cuam tshuam DPP - 4 kev ua ub no (Hinke li al 2002).
Xav txog qhov no, Puas yog Metformin yog DPP 4 tshuaj?
Cov tshuaj nyob hauv DPP - 4 ua inhibitor Cov chav kawm suav nrog sitagliptin, saxagliptin, linagliptin, thiab alogliptin. Lawv muaj raws li cov khoom lag luam ib leeg thiab ua ke nrog lwm cov tshuaj mob ntshav qab zib xws li metformin tshuaj (saib Cov Lus 1 hauv seem Kev Nyab Xeeb Kev Tshaj Tawm rau tag nrho cov npe ntawm FDA-pom zoo DPP - 4 inhibitors).
Ib qho ntxiv, cov tshuaj dab tsi yog dpp4? Tshuaj nyob hauv chav kawm no
- Januvia (Sitagliptin) tshuaj
- Galvus (Vildagliptin)
- Onglyza (Saxagliptin)
- Tradjenta (Linagliptin) - pom zoo siv hauv Asmeskas.
Cov lus nug tseem yog, DPP 4 inhibitor hauv ntshav qab zib yog dab tsi?
Dipeptidyl peptidase 4 ( DPP - 4 ) inhibitors yog ib chav kawm ntawm cov tshuaj uas txo qis cov ntshav qab zib ntau ntau thiab tuaj yeem siv hauv kev kho hom 2 mob ntshav qab zib . Lawv feem ntau tsis ua rau cov ntshav qab zib tsawg (cov ntshav qab zib tsawg) tshwj tsis yog lawv tau ua ke nrog lwm cov kev kho mob uas ua rau cov ntshav qab zib tsawg.
DPP 4 inhibitors ua haujlwm li cas?
DPP - 4 cov tshuaj tiv thaiv (gliptins) tshuaj DPP - 4 inhibitors ua haujlwm los ntawm thaiv qhov kev nqis tes ua ntawm DPP - 4 , ib qho enzyme uas rhuav tshem cov tshuaj hormone incretin. Incretins pab lub cev tsim cov tshuaj insulin ntau ntxiv tsuas yog thaum nws xav tau thiab txo qis cov piam thaj tau tsim los ntawm lub siab thaum nws tsis xav tau.
Pom zoo:
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Cov khoom xyaw nquag yog candesartan cilexetil. Qhov no yog ib pawg ntawm cov tshuaj hu ua angiotensin II receptor antagonists. Nws ua haujlwm los ntawm kev ua kom koj cov hlab ntshav so thiab nthuav dav. (ACE-inhibitors thiab MRAs yog cov tshuaj siv los kho lub plawv tsis ua haujlwm)
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Fluconazole yog ib qho inhibitor ntawm CYP3A4, CYP2C9 thiab 2C19 enzymes tab sis tsis yog inhibitor ntawm cov neeg thauj khoom [10, 12, 15]. Yog li, qhov cuam tshuam ntawm fluconazole ntawm PK ntawm 5-HMT yuav raug suav hais tias yog tus sawv cev ntawm kev sib cuam tshuam ntawm CYP3A4 inhibitors nruab nrab nrog fesoterodine
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Amlodipine Besylate Yog Qhov Ua Tau Zoo ACE Inhibitor. Paub tias yog lub npe lag luam Lotrel, Amlodipine Besylate ua lub luag haujlwm tseem ceeb ntawm qhov muaj zog calcium channel blocker. Cov kev mob tshwm sim ntawm amlodipine besylate raws li ib feem ntawm Lotrel yog me me, thiab tej zaum yuav muaj mob taub hau, hnoos, kiv taub hau thiab o ntawm cov extremities
Puas yog germaphobe puas yog kev puas siab puas ntsws?
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Kev cai huv huv Germaphobes lub neej. Germaphobes muaj kev nyiam huv nrog kev huv thiab xav tias yuav tsum tau ntxuav ntau dhau, tab sis lawv tau raug kev txom nyem tiag tiag los ntawm kev tsis quav ntsej-yuam kev. Tib neeg feem ntau muaj ntau hom ntaub ntawv ntawm OCD
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Thaum cov tshuaj tiv thaiv kab mob thim rov qab mus rau qhov chaw nquag ntawm cov enzyme nws yog lub npe hu ua COMPETITIVE INHIBITOR. Hauv qhov kev sim no koj yuav siv cov enzyme β-galactosidase. Nws cov substrate ib txwm yog lactose tab sis koj yuav siv cov hluavtaws substrate, ONPG