Puas yog cov pob txha mos pob txha calcified?

2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44

Thaum lub sijhawm txhim kho, thawj qhov no pob txha mos feem ntau hloov los ntawm endochondral pob txha via ib calcification txheej txheem (paub tias yog endochondral ossification) uas cuam tshuam nrog kev hloov pauv hnyav rau cov ntaub so ntswg, cov xov tooj ntawm tes thiab cov protein qhia, txheeb ze rau qhov uas tau pom hauv kev so pob txha mos.

Ib yam li ib tus yuav nug, dab tsi yog calcified pob txha mos?

Calcified pob txha mos cheeb tsam (CCZ) yog ib qho sib txuam ua ke ntawm cov ntaub so ntswg nyuaj, nruab nrab ntawm cov pob txha hyaline pob txha mos thiab pob txha subchondral (1). Hyaline pob txha mos yog txuas rau cov pob txha subchondral los ntawm thaj tsam cov ntxhia no.

Ib yam li ntawd, cov pob txha puas muaj calcium? Pob txha mos , zoo li pob txha, nyob ib puag ncig los ntawm perichondrium-zoo li fibrous membrane. Qhov no yog ua raws los ntawm kev hloov pauv pob txha mos nrog cov nqaij zoo li pob txha. Tsis zoo li pob txha, pob txha mos tsis muaj calcium hauv matrix. Hloov chaw, nws muaj ntau ntau ntawm chondroitin, uas yog cov khoom siv uas muab kev ywj pheej thiab yoog raws.

Hauv txoj kev no, qhov sib txawv ntawm cov pob txha mos thiab cov pob txha yog dab tsi?

Nkawd ob leeg tau ua tiav ntawm hlwb kos hauv ib extracellular matrix. Nws yog qhov xwm txheej ntawm matrix uas qhia txog cov khoom ntawm cov ntaub so ntswg sib txuas. Pob txha mos yog nyias, avascular, yoog raws thiab tiv taus cov quab yuam. Pob txha nws yog vascularized heev, thiab nws calcified matrix ua rau nws muaj zog heev.

Yuav ua li cas pob txha mos dhau los ua calcified?

Cov calcified pob txha mos cheeb tsam: chondrocytes raug apoptosis, septa nyias ntawm pob txha mos matrix ua calcified . Thaj chaw ossification: cov nqaij pob txha endochondral tshwm. Cov ntshav capillaries thiab cov pob txha osteoprogenitor (los ntawm periosteum) nkag mus rau kab noj hniav sab laug los ntawm chondrocytes.