Pulsatile yam yog dab tsi?
Pulsatile yam yog dab tsi?

Video: Pulsatile yam yog dab tsi?

Video: Pulsatile yam yog dab tsi?
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Pulsatile kev tso dej tawm yog ib qho tshwm sim ntawm cov tshuaj lom neeg, xws li cov tshuaj hormone, tau zais hauv qhov tawg zoo li lossis episodic yam tsis tas li. Piv txwv ntawm cov tshuaj hormones uas secreted pulsatilely muaj xws li gonadotropin-tso hormone (GnRH) thiab loj hlob hormone (GH).

Ib yam li ntawd, koj tuaj yeem nug, vim li cas GnRH pulsatile?

Cov pulsatile tso tawm ntawm GnRH thiab LH ua lub luag haujlwm tseem ceeb hauv kev txhim kho kev sib deev thiab hauv kev tswj hwm ib txwm muaj ntawm kev coj khaub ncaws. Ib qho laj thawj rau GnRH secretion hauv ib pulsatile yam yog kom tsis txhob down-txoj cai ntawm lub GnRH receptor nyob rau hauv lub caj pas pituitary.

Ntxiv mus, GnRH mem tes yog dab tsi? Hauv cov txiv neej, GnRH yog secreted hauv mem tes ntawm qhov zaus; txawm li cas los xij, hauv poj niam, qhov zaus ntawm noob taum sib txawv thaum lub caij coj khaub ncaws, thiab muaj qhov nce loj ntawm GnRH ua ntej ovulation. GnRH Kev tso tawm yog pulsatile nyob rau hauv tag nrho cov vertebrates, thiab yog qhov tsim nyog rau kev ua me nyuam kom raug.

Ntawm no, dab tsi ua rau tso GnRH?

GnRH yog ib yam tshuaj tsim tawm hauv cheeb tsam hypothalamus ntawm lub paj hlwb. GnRH txav los ntawm cov hlab ntsha mus rau lub caj pas pituitary. Nyob ntawd, nws khi rau qee yam receptors. Cov receptors qhia lub caj pas pituitary los tsim ob yam tshuaj hormones ntxiv: LH thiab follicle-stimulating hormone (FSH).

Dab tsi ua rau hypothalamus tso GnRH?

Kisspeptin qhia ncaj qha rau hypothalamic GnRH neurons ntawm tus kisspeptin receptor rau tso GnRH mus rau hauv lub portal ncig, uas nyob rau hauv lem txhawb nqa anterior pituitary gonadotrophs los tsim LH thiab FSH (121, 141).

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