Video: Yuav ua li cas microglia qhib?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Microglia tau koom ua ke zoo hauv cov neuronal glial network ntawm kev noj qab haus huv CNS. Feem ntau, ua kom microglia tau tshwm sim los ntawm plethora ntawm cov lus piav qhia zoo ntawm cov neeg txais kev tiv thaiv kab mob xws li Toll-like receptors (TLRs), cov neeg txais khoom noj, thiab ntau tus cytokine thiab chemokine receptors.
Ntxiv mus, dab tsi tshwm sim thaum microglia tau qhib?
Qhib microglia tsim thiab tso tawm ntau yam molecules teb rau ntau qhov stimuli los ntawm ib puag ncig. Cell tuag ua rau muaj kev hloov pauv ntxiv ntawm microglia mus rau hauv phagocytic cells. Qhib microglia kuj tseem cuam tshuam nrog cov cell tiv thaiv kab mob nkag los ntawm cov ntshav -hlwb teeb meem.
Tom qab ntawd, lo lus nug yog, microglia tsim tawm qhov twg? Microglia suav txog 10-15% ntawm txhua lub cell pom hauv lub hlwb. Raws li cov neeg nyob hauv macrophage hlwb, lawv ua thawj thiab tseem ceeb ntawm kev tiv thaiv kev tiv thaiv kab mob hauv nruab nrab paj hlwb (CNS). Microglia (thiab lwm yam neuroglia suav nrog astrocytes) tau faib rau hauv thaj tsam loj tsis sib tshooj thoob plaws hauv CNS.
Hauv qhov no, lub luag haujlwm ntawm microglial hlwb yog dab tsi?
Microglial hlwb yog cov neeg tshwj xeeb ntawm macrophages uas pom nyob rau hauv lub hauv paus paj hlwb (CNS). Lawv tshem tawm cov neurons puas thiab kis kab mob thiab tseem ceeb rau kev tswj hwm kev noj qab haus huv ntawm CNS.
Puas yog microglia ua rau mob?
Microglial cov cell muaj lub luag haujlwm saib xyuas kev tiv thaiv kab mob hauv CNS. Lawv teb rau qhov tsis txaus siab stimuli los ntawm kev tso tawm mob cov kws kho mob nruab nrab thiab ua kom muaj txiaj ntsig zoo mob lus teb Neuropeptides ua tau kuj cuam tshuam mob cov lus teb thiab mob rhiab heev los ntawm kev hloov kho cov haujlwm ntawm glial hlwb.
Pom zoo:
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