Video: Puas yog BCR yog tshuaj tiv thaiv?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
Los ntawm kev txheeb xyuas biochemical thiab los ntawm lub cev tau txais antigens los ntawm kev tiv thaiv kab mob sib kis, BCR tswj kev ua haujlwm ntawm B cell. Tus neeg txais kev khi txoj hlua khi yog tsim los ntawm daim nyias nyias tshuaj tiv thaiv uas, zoo li tag nrho tshuaj tiv thaiv , muaj qhov tshwj xeeb thiab txiav txim siab qhov chaw tiv thaiv kab mob antigen.
Hauv qhov no, qhov sib txawv ntawm BCR thiab cov tshuaj tiv thaiv kab mob zais los ntawm tib lub cell B yog dab tsi?
B cell receptors rau antigen yuav luag zoo ib yam nyob rau hauv qauv rau zais cov tshuaj tiv thaiv . Tus qauv nkaus xwb sib txawv yog tias thaj tsam C-davhlau ya nyob twg ntawm cov saw hlau hnyav muaj qhov ua kom luv hydrophobic uas nthuav tawm lipid bilayer ntawm daim nyias nyias.
Ib yam nkaus, lub luag haujlwm ntawm cov tshuaj tiv thaiv kab mob yog dab tsi? Ib tshuaj tiv thaiv , tseem paub tias yog immunoglobulin, yog cov protein loj uas zoo li Y tsim los ntawm B-cells thiab siv los ntawm lub cev tiv thaiv kab mob txhawm rau txheeb xyuas thiab nruab nrab cov khoom txawv teb chaws xws li cov kab mob thiab kab mob. Tsib isotypes ntawm tshuaj tiv thaiv muaj nyob rau hauv ntau qhov chaw thiab ua haujlwm sib txawv.
Hais txog qhov no, qib twg ntawm immunoglobulins tuaj yeem siv ua BCR?
Immunoglobulin D IgD yog ib qho monomer nrog qhov hnyav ntawm 184 Kd. IgD uas muaj nyob rau hauv ib tug meager npaum li cas nyob rau hauv cov ntshav (0.03 mg / mL) thiab muaj ib tug tsis paub ua hauj lwm tiv thaiv kab mob. Nws yog suav tias yog ib qho BCR . IgD tuaj yeem ua lub luag haujlwm tseem ceeb hauv antigen-triggered lymphocyte sib txawv.
Dab tsi yog qhov txawv ntawm ib qho antigen thiab antibody?
Antigens yog cov lwg me me muaj peev xwm txhawb kev tiv thaiv kab mob. Txhua antigen muaj qhov sib txawv ntawm qhov chaw, lossis epitopes, ua rau cov lus teb tshwj xeeb. Cov tshuaj tiv thaiv (immunoglobins) yog cov protein zoo li Y tsim los ntawm B cells ntawm lub cev tiv thaiv kab mob los teb rau kis antigens.
Pom zoo:
Qhov twg ntawm cov tshuaj tiv thaiv hauv qab no yog siv rau kev txhaj tshuaj tiv thaiv kab mob?
Passive Immunization DISEASE NAME OF MATERIAL Cytomegalovirus Cytomegalovirus immun globulin, txhaj tshuaj tiv thaiv kab mob Diphtheria Diphtheria antitoxin, equine Rabies Rabies tiv thaiv globulin, tib neeg Measles Immune globulin, tib neeg
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