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Video: Cov tshuaj twg yog alpha 2 agonists?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2024-01-18 09:28
Alpha-2 agonists
- Clonidine ( Catapres ®)
- Clonidine thaj ( Catapres-TSO ®)
- Methyldopa (Aldomet®)
- Tizanidine (Zanaflex®) - siv los ua cov leeg nqaij.
- Clonidine ( Kapvay ®) - siv los kho ADHD.
- Guanfacine ( Intuniv ®) - siv los kho ADHD.
- Lofexidine (Lucemyra ™) - FDA tau pom zoo los kho kev quav yeeb quav tshuaj.
Tom qab ntawd, cov tshuaj twg yog alpha agonists?
Xaiv cov piv txwv yog:
- Clonidine (sib xyaw alpha2-adrenergic thiab imidazoline-I1 receptor agonist)
- Dexmedetomidine.
- Fadolmidine.
- Guanfacine (xws li alpha2A-subtype ntawm adrenoceptor)
- Guanabenz (feem ntau xaiv agonist rau alpha2-adrenergic as opposed to imidazoline-I1)
- Guanoxabenz (metabolite ntawm guanabenz)
Tsis tas li ntawd, alpha 2 agonists ua rau sedation li cas? Sedative teebmeem Alpha2 - agonists khi nrog thiab intrinsically hloov cov membranes ntawm lub α2 -adrenoreceptors, tiv thaiv kev tso tawm ntxiv ntawm cov neurotransmitter norepinephrine. Hauv nruab nrab, norepinephrine yog qhov tsim nyog rau kev txhawb siab. Yog tias qhov tso tawm ntawm norepinephrine raug thaiv, qhov txiaj ntsig tau yog sedation.
Yog li ntawd, alpha 2 agonists ua dab tsi?
Alpha 2 receptors nyob rau hauv lub paj hlwb thiab nyob ib puag ncig cuam tshuam kev ua siab zoo thiab yog li ua rau cov ntshav siab. Alpha 2 tus txais agonists xws li clonidine los yog guanabenz txo qhov nruab nrab thiab peripheral sympathetic overflow thiab ntawm peripheral presynaptic receptors yuav txo tau peripheral neurotransmitter tso tawm.
Puas yog Xylazine yog alpha 2 agonist?
Alpha - 2 cov agonists tau ua tiav cov neeg nyiam nyob hauv cov tshuaj veterinary rau lawv cov sedative thiab analgesic zog. Xylazine, ib qho alpha - 2 agonist nrog sib xyaw alpha -1 thiab cov tshuaj loog hauv zos ib yam li alpha - 2 selectivity, tau siv los ntawm kws kho tsiaj rau ntau xyoo hauv ntau hom.
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