Video: Th2 cell yog dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
T pab hom 2 ( Th2 ) hlwb yog ib hom kab mob sib txawv ntawm CD4+ effector T ntawm tes uas secretes IL-4, IL-5, IL-9, IL-13, thiab IL-17E/IL-25. Cov no hlwb yuav tsum muaj rau kev tiv thaiv kev lim hiam thiab ua lub luag haujlwm tseem ceeb hauv kev sib koom tes tiv thaiv kev tiv thaiv kab mob rau cov kab mob loj sab nraud.
Ib yam li ntawd, koj tuaj yeem nug, qhov txawv ntawm th1 thiab th2 hlwb yog dab tsi?
Ob tug pab T ntawm tes cov chav kawm kuj txawv ntawm hom kev tiv thaiv kab mob uas lawv tsim. Thaum Th1 cev yuav tsim cov lus teb tiv thaiv kab mob hauv lub cev xws li kab mob thiab kab mob, Th2 cev tsim cov lus teb tiv thaiv kab mob helminths thiab lwm yam kab mob sab nraud.
Qhov thib ob, dab tsi ua rau th2? Th 2 cov cell tau tsim thaum CD4+ TN cov hlwb tau pib ua ntej thaum muaj IL-4. Qhov no cytokine induces lub Th2 master transcription factor GATA-3, uas ntawm nws tig induces zus tau tej cov Th2 -cytokines IL-4, IL-5, thiab IL-13 (Zheng thiab Flavell, 1997; Lantelme li al., 2001).
Tom qab ntawd, lo lus nug yog, th2 txhais li cas?
Kev kho mob Txhais ntawm Th2 Th2 : T hlwb tejzaum nws cuam tshuam nrog poliferation ntawm cytokines. Saib: T-helper cell.
Puas yog th2 cells tiv thaiv kev mob?
Cov Th 2 -type cytokines muaj xws li interleukins 4, 5, thiab 13, uas cuam tshuam nrog kev txhawb nqa ntawm IgE thiab eosinophilic cov lus teb hauv atopy, thiab tseem muaj interleukin-10, uas muaj ntau dua ntawm cov lus teb ntawm eosinophilic. tiv thaiv - mob lus teb Tshaj dhau, Th2 Cov lus teb yuav tawm tsam Th1 mediated microbicidal action.
Pom zoo:
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