Yuav ua li cas Imodium metabolized?

Video: Yuav ua li cas Imodium metabolized?

2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44

Loperamide yog P-glycoprotein substrate. Tshem Tawm Qhov pom tseeb tshem tawm ib nrab ntawm lub neej tshuaj loperamide yog 10.8 teev nrog ntau yam ntawm 9.1 txog 14.4 teev. Metabolism Hauv vitro tshuaj loperamide yog metabolized Feem ntau yog los ntawm cytochrome P450 (CYP450) isozymes, CYP2C8 thiab CYP3A4, tsim- N-demethyl tshuaj loperamide.

Hauv kev hais txog qhov no, Imodium raug tso tawm li cas?

Loperamide yog tso tawm los ntawm cov kab ke ntawm tib neeg feem ntau los ntawm cov quav. Raws li qhov nruab nrab ib nrab-lub neej kwv yees ntawm 10.8 teev, nws tuaj yeem siv li 54 teev rau tag nrho cov koob tshuaj. Imodium tawm ntawm qhov system ntawm tus coj.

Tsis tas li ntawd, Imodium puas ua rau lub siab puas tsuaj? Siab muaj nuj nqi: Loperamide yog tawg los ntawm daim siab . Kab mob siab los yog txo daim siab muaj nuj nqi ua cov tshuaj no los txhim kho lub cev, ua rau kev mob tshwm sim. Cov tshuaj no kuj yuav ua kev txo qis hauv daim siab muaj nuj nqi

Tib neeg kuj nug, Imodium ua li cas rau koj lub cev?

Cov tshuaj no yog siv los kho mob raws plab sai sai (suav nrog cov neeg taug kev raws plab). Nws ua haujlwm los ntawm kev qeeb qeeb cov zog ntawm plab. Qhov no txo qis cov tus lej ntawm plab hnyuv thiab ua cov quav dej tsawg. Loperamide kuj yog siv los txo cov tus nqi ntawm tso tawm hauv cov neeg mob uas tau txais ib qho ileostomy.

Cov kev phom sij ntawm kev noj ntau npaum li cas Imodium?

Cov tsos mob ntawm Imodium ntau dhau yuav suav nrog kiv taub hau, tsaug zog tso zis tsawg dua li niaj zaus, tsam plab, mob plab hnyav, lossis ntuav.

Pom zoo:

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Puas yog cov tshuaj IV metabolized los ntawm daim siab?

Rau kev txhaj tshuaj ntawm cov tshuaj, bioavailability yog sib npaug (100%). Cov tshuaj tuaj yeem ua rau cov metabolism hauv cov phab ntsa hauv plab, tab sis feem ntau hauv lub siab uas yog lub luag haujlwm rau cov metabolism hauv ua ntej cov tshuaj mus txog qhov ua haujlwm ntawm cov hlab ntshav

Cov tshuaj metabolized li cas?

Feem ntau cov tshuaj yuav tsum dhau los ntawm daim siab, uas yog qhov chaw tseem ceeb rau cov tshuaj metabolism. Ib zaug nyob rau hauv daim siab, enzymes hloov prodrugs mus rau active metabolites los yog hloov active tshuaj mus rau inactive cov ntaub ntawv. Lub siab lub hauv paus tseem ceeb rau kev zom cov tshuaj yog los ntawm cov pab pawg tshwj xeeb ntawm cytochrome P-450 enzymes

Methimazole metabolized li cas?

Methimazole inhibits synthesis ntawm cov thyroid hormones thiab yog li muaj txiaj ntsig zoo hauv kev kho mob hyperthyroidism. Methimazole tau nkag mus rau hauv lub plab zom mov, metabolized hauv daim siab, thiab tawm hauv cov zis