Video: Lub luag haujlwm ntawm c3b yog dab tsi?
2024 Tus sau: Michael Samuels | [email protected]. Kawg hloov kho: 2023-12-16 01:44
C3b yog qhov loj ntawm ob lub ntsiab lus tsim los ntawm kev sib cais ntawm kev sib xyaw ua ke 3, thiab suav tias yog ib feem tseem ceeb ntawm lub cev tiv thaiv kab mob. C3b muaj zog hauv opsonization: cim cov kab mob, tiv thaiv kab mob (antigen-antibody), thiab apoptotic cells rau phagocytosis.
Raws li, c3b yog Opsonin?
Innate Immunity Cov C3b hais tias ua yeeb yam opsonin nyob rau hauv cov ntaub ntawv no vim hais tias nws txhim khu lub peev xwm ntawm ib qho chaw rau phagocytosed. Los ntawm kev txhawb nqa kev kis kab mob los ntawm APCs hauv txoj kev no, C3b indirectly txhim kho antigen kev nthuav qhia rau T hlwb thiab yog li cov lus teb hloov.
Kuj Paub, c3a thiab c5a ua dab tsi? C3a thiab C5a , qhov me me (kwv yees li 10KDa) qhov tawg tawg tawm los ntawm kev ua kom tiav, yog cov kws kho mob muaj zog ntawm kev mob. Lawv yog cov tshuaj anaphylatoxins thiab ua lub cell activators nrog nanomolar affinity, ua haujlwm lawv los ntawm kev khi rau cov neeg txais tshwj xeeb (C3aR thiab C5aR lossis C5L2 feem).
Kuj Paub, c3a ua haujlwm yog dab tsi?
C3a yog ib qho ntawm cov proteins uas tsim los ntawm cleavage ntawm complement 3; lwm tus yog C3b. C3a yog qhov cuam tshuam ntawm kev ua tiav nrog ntau yam ntawm kev ua haujlwm suav nrog T cell ua kom muaj sia nyob thiab muaj sia nyob, stimulation angiogenesis, chemotaxis, mast cell degranulation, thiab macrophage activation.
Vim li cas c3 tseem ceeb?
Cov proteins no yog ib feem ntawm koj qhov system ntxiv, ib qho tseem ceeb ib feem ntawm koj lub cev tiv thaiv kab mob uas pab tua kab mob ua rau muaj kab mob thiab kab mob. Complement tivthaiv C3 yog feem ntau tseem ceeb thiab muaj protein ntau nyob rau hauv lub complement system. Nws tau muab tso rau ntawm microbes kom rhuav tshem lawv.
Pom zoo:
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